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10.1155/2018/9682801

http://scihub22266oqcxt.onion/10.1155/2018/9682801
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suck abstract from ncbi

pmid29971178
      Case+Rep+Rheumatol 2018 ; 2018 (?): 9682801
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  • Aortic Aneurysm as a Complication of Granulomatosis with Polyangiitis Successfully Treated with Prednisolone and Cyclophosphamide: A Case Report and Review of the Literature #MMPMID29971178
  • Niimi N ; Miyashita T ; Tanji K ; Hirai T ; Watanabe K ; Ikeda K ; Morimoto S ; Sekigawa I
  • Case Rep Rheumatol 2018[]; 2018 (?): 9682801 PMID29971178 show ga
  • A 57-year-old Japanese man was admitted to the hospital with back pain and fever, multiple lung nodules, and abdominal aortic aneurysm (AAA). Laboratory tests performed at admission showed an increased proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) level. Video-associated thoracoscopic lung biopsy was performed; pathologic examination showed granulation tissue with necrosis and multinucleated giant cells. The diagnosis of granulomatosis with polyangiitis (GPA) was confirmed on the basis of the clinical presentation, laboratory findings, and lung biopsy. All symptoms were ameliorated, and the serum level of PR3-ANCA declined following treatment with prednisolone and cyclophosphamide. Although the association of GPA with AAA is rare, GPA may be included among the large vessel vasculitides that can give rise to aortic aneurysm.
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