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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 CBE+Life+Sci+Educ
2018 ; 17
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): ä Nephropedia Template TP
gab.com Text
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English Wikipedia
How Four Scientists Integrate Thermodynamic and Kinetic Theory, Context,
Analogies, and Methods in Protein-Folding and Dynamics Research: Implications for
Biochemistry Instruction
#MMPMID29440073
Jeffery KA
; Pelaez N
; Anderson TR
CBE Life Sci Educ
2018[Spr]; 17
(1
): ä PMID29440073
show ga
To keep biochemistry instruction current and relevant, it is crucial to expose
students to cutting-edge scientific research and how experts reason about
processes governed by thermodynamics and kinetics such as protein folding and
dynamics. This study focuses on how experts explain their research into this
topic with the intention of informing instruction. Previous research has modeled
how expert biologists incorporate research methods, social or biological context,
and analogies when they talk about their research on mechanisms. We used this
model as a guiding framework to collect and analyze interview data from four
experts. The similarities and differences that emerged from analysis indicate
that all experts integrated theoretical knowledge with their research context,
methods, and analogies when they explained how phenomena operate, in particular
by mapping phenomena to mathematical models; they explored different processes
depending on their explanatory aims, but readily transitioned between different
perspectives and explanatory models; and they explained thermodynamic and kinetic
concepts of relevance to protein folding in different ways that aligned with
their particular research methods. We discuss how these findings have important
implications for teaching and future educational research.