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10.3390/cancers10050137 http://scihub22266oqcxt.onion/10.3390/cancers10050137 C5977110!5977110!29734788     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancers+(Basel) 2018 ; 10 (5): ä Nephropedia Template TP {{tp|p=29734788|t=2018. YAP and TAZ in Lung Cancer: Oncogenic Role and Clinical Targeting |pdf=|usr=}}{{29734788}} gab.com Text YAP and TAZ in Lung Cancer: Oncogenic Role and Clinical Targeting JO: Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=29734788 #FOAvip Lung cancer is the leading cause of cancer death in the world and there is no current treatment able to efficiently treat the disease as the tumor is often diagnosed at an advanced stage. Moreover, cancer cells are often resistant or acquire resistance to the treatment. Further knowledge of the mechanisms driving lung tumorigenesis, aggressiveness, metastasization, and resistance to treatments could provide new tools for detecting the disease at an earlier stage and for a better response to therapy. In this scenario, Yes Associated Protein (YAP) and Trascriptional Coactivator with PDZ-binding motif (TAZ), the final effectors of the Hippo signaling transduction pathway, are emerging as promising therapeutic targets. Here, we will discuss the most recent advances made in YAP and TAZ biology in lung cancer and, more importantly, on the newly discovered mechanisms of YAP and TAZ inhibition in lung cancer as well as their clinical implications. Twit Text FOAVip YAP and TAZ in Lung Cancer: Oncogenic Role and Clinical Targeting ????Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=29734788 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29734788 #FOAvip English Wikipedia <ref>{{Cite pmid|29734788}}</ref> YAP and TAZ in Lung Cancer: Oncogenic Role and Clinical Targeting #MMPMID29734788 Lo Sardo F; Strano S; Blandino G Cancers (Basel) 2018[May]; 10 (5): ä PMID29734788show ga Lung cancer is the leading cause of cancer death in the world and there is no current treatment able to efficiently treat the disease as the tumor is often diagnosed at an advanced stage. Moreover, cancer cells are often resistant or acquire resistance to the treatment. Further knowledge of the mechanisms driving lung tumorigenesis, aggressiveness, metastasization, and resistance to treatments could provide new tools for detecting the disease at an earlier stage and for a better response to therapy. In this scenario, Yes Associated Protein (YAP) and Trascriptional Coactivator with PDZ-binding motif (TAZ), the final effectors of the Hippo signaling transduction pathway, are emerging as promising therapeutic targets. Here, we will discuss the most recent advances made in YAP and TAZ biology in lung cancer and, more importantly, on the newly discovered mechanisms of YAP and TAZ inhibition in lung cancer as well as their clinical implications. äYAP and TAZ in Lung Cancer: Oncogenic Role and Clinical Targeting (epmc).pdf DeepDyve Pubget Overpricing