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2018 ; 10
(3
): e2398
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Efficacy of Hemocoagulase as a Topical Hemostatic Agent After Dental Extractions:
A Systematic Review
#MMPMID29854573
Gupta G
; M R M
; Kumar SP
Cureus
2018[Mar]; 10
(3
): e2398
PMID29854573
show ga
Extraction is one of the more common oral surgical procedures carried out in
routine dental practice, and postextraction bleeding is a recognized, frequently
encountered complication. It causes distress, agony, and discomfort to the
patient. The aim of this systematic review was to analyze the existing literature
and determine the efficacy of topical hemocoagulase as a hemostatic agent and its
ability to reduce postoperative complications in comparison to routine saline
pressure pack after the extraction of teeth. Information was collected from an
electronic database (PubMed), and a manual search was also done in Oral Surgery,
Oral Medicine, Oral Pathology, Oral Radiology; International Journal of Oral and
Maxillofacial Surgery; and the British Journal of Oral and Maxillofacial Surgery.
Only those articles which met the inclusion criteria were selected. All studies
and articles that compared topical hemocoagulase with saline pressure pack in
patients requiring extraction of teeth were selected for review. Literature
abstracts and full-text articles were analysed in this review. A total of four
articles were included in this systematic review. All were randomized clinical
trials that evaluated the clinical outcomes of topical hemocoagulase compared
with saline pressure packs in extraction socket sites. A significant difference
was present between the hemocoagulase group and control group (saline pressure
pack) in relation to bleeding stoppage time, pain, swelling, wound healing, and
other postoperative complications. Topical hemocoagulase is significantly
effective in reducing bleeding, pain, and swelling after extraction of tooth when
compared to saline pressure packs. It also acts as a promoter of wound healing.