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10.1080/19491034.2017.1414118 http://scihub22266oqcxt.onion/10.1080/19491034.2017.1414118 C5973264!5973264!29227210     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nucleus 2018 ; 9 (1): 119-24 Nephropedia Template TP {{tp|p=29227210|t=2018. Separate roles for chromatin and lamins in nuclear mechanics |pdf=|usr=}}{{29227210}} gab.com Text Separate roles for chromatin and lamins in nuclear mechanics JO: Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=29227210 #FOAvip The cell nucleus houses, protects, and arranges the genome within the cell. Therefore, nuclear mechanics and morphology are important for dictating gene regulation, and these properties are perturbed in many human diseases, such as cancers and progerias. The field of nuclear mechanics has long been dominated by studies of the nuclear lamina, the intermediate filament shell residing just beneath the nuclear membrane. However, a growing body of work shows that chromatin and chromatin-related factors within the nucleus are an essential part of the mechanical response of the cell nucleus to forces. Recently, our group demonstrated that chromatin and the lamina provide distinct mechanical contributions to nuclear mechanical response. The lamina is indeed important for robust response to large, whole-nucleus stresses, but chromatin dominates the short-extension response. These findings offer a clarifying perspective on varied nuclear mechanics measurements and observations, and they suggest several new exciting possibilities for understanding nuclear morphology, organization, and mechanics. Twit Text FOAVip Separate roles for chromatin and lamins in nuclear mechanics ????Nucleus http://www.kidney.de/pget.php?&tw=1&pmid=29227210 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29227210 #FOAvip English Wikipedia <ref>{{Cite pmid|29227210}}</ref> Separate roles for chromatin and lamins in nuclear mechanics #MMPMID29227210 Stephens AD; Banigan EJ; Marko JF Nucleus 2018[]; 9 (1): 119-24 PMID29227210show ga The cell nucleus houses, protects, and arranges the genome within the cell. Therefore, nuclear mechanics and morphology are important for dictating gene regulation, and these properties are perturbed in many human diseases, such as cancers and progerias. The field of nuclear mechanics has long been dominated by studies of the nuclear lamina, the intermediate filament shell residing just beneath the nuclear membrane. However, a growing body of work shows that chromatin and chromatin-related factors within the nucleus are an essential part of the mechanical response of the cell nucleus to forces. Recently, our group demonstrated that chromatin and the lamina provide distinct mechanical contributions to nuclear mechanical response. The lamina is indeed important for robust response to large, whole-nucleus stresses, but chromatin dominates the short-extension response. These findings offer a clarifying perspective on varied nuclear mechanics measurements and observations, and they suggest several new exciting possibilities for understanding nuclear morphology, organization, and mechanics. äSeparate roles for chromatin and lamins in nuclear mechanics (epmc).pdf DeepDyve Pubget Overpricing