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10.1016/j.kint.2018.01.012

http://scihub22266oqcxt.onion/10.1016/j.kint.2018.01.012
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C5972550!5972550!29680019
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suck abstract from ncbi


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pmid29680019      Kidney+Int 2018 ; 93 (5): 1038-40
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  • Unraveling the mechanisms of obesity-induced hyperoxaluria #MMPMID29680019
  • Sakhaee K
  • Kidney Int 2018[May]; 93 (5): 1038-40 PMID29680019show ga
  • Kidney stones is increasingly associated with obesity. With an increasing prevalence of obesity and metabolic syndrome in the past 30 years, urinary oxalate has significantly increased. However, its underlying pathophysiologic mechanisms of hyperoxaluria have not been fully explored. This preclinical study suggests that hyperoxaluria in obesity depends on a complex network of inflammatory responses linked to metabolic outcome. The future mechanistic and clinical investigations must be targeted at elucidating the pathogenetic role of inflammation in obesity induced hyperoxaluria.
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