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10.1208/s12248-017-0079-3 http://scihub22266oqcxt.onion/10.1208/s12248-017-0079-3 C5972029!5972029 !28397097     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28397097 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       AAPS+J 2017 ; 19 (4 ): 921-930 Nephropedia Template TP {{tp|p=28397097 |t=2017. Blood-Brain Barriers in Obesity |pdf=|usr=}}{{28397097 }} gab.com Text Blood-Brain Barriers in Obesity JO: AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=28397097 #FOAvip After decades of rapid increase, the rate of obesity in adults in the USA is beginning to slow and the rate of childhood obesity is stabilizing. Despite these improvements, the obesity epidemic continues to be a major health and financial burden. Obesity is associated with serious negative health outcomes such as cardiovascular disease, type II diabetes, and, more recently, cognitive decline and various neurodegenerative dementias such as Alzheimer's disease. In the past decade, major advancements have contributed to the understanding of the role of the central nervous system (CNS) in the development of obesity and how peripheral hormonal signals modulate CNS regulation of energy homeostasis. In this article, we address how obesity affects the structure and function of the blood-brain barrier (BBB), the impact of obesity on Alzheimer's disease, the effects of obesity on circulating proteins and their transport into the brain, and how these changes can potentially be reversed by weight loss. Twit Text FOAVip Blood-Brain Barriers in Obesity ????AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=28397097 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28397097 #FOAvip English Wikipedia <ref>{{Cite pmid|28397097 }}</ref> Blood-Brain Barriers in Obesity #MMPMID28397097 Rhea EM ; Salameh TS ; Logsdon AF ; Hanson AJ ; Erickson MA ; Banks WA AAPS J 2017[Jul]; 19 (4 ): 921-930 PMID28397097 show ga After decades of rapid increase, the rate of obesity in adults in the USA is beginning to slow and the rate of childhood obesity is stabilizing. Despite these improvements, the obesity epidemic continues to be a major health and financial burden. Obesity is associated with serious negative health outcomes such as cardiovascular disease, type II diabetes, and, more recently, cognitive decline and various neurodegenerative dementias such as Alzheimer's disease. In the past decade, major advancements have contributed to the understanding of the role of the central nervous system (CNS) in the development of obesity and how peripheral hormonal signals modulate CNS regulation of energy homeostasis. In this article, we address how obesity affects the structure and function of the blood-brain barrier (BBB), the impact of obesity on Alzheimer's disease, the effects of obesity on circulating proteins and their transport into the brain, and how these changes can potentially be reversed by weight loss. |*Blood-Brain Barrier [MESH] |Alzheimer Disease/physiopathology [MESH] |Central Nervous System/pathology/physiopathology [MESH] |Hormones/physiology [MESH] |Humans [MESH] |Inflammation/physiopathology [MESH]Blood-Brain Barriers in Obesity (epmc).pdf DeepDyve Pubget Overpricing