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10.1038/s41598-018-26531-0

http://scihub22266oqcxt.onion/10.1038/s41598-018-26531-0
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C5970155!5970155!29802350
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suck abstract from ncbi


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pmid29802350      Sci+Rep 2018 ; 8 (ä): ä
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  • Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis #MMPMID29802350
  • Joshita S; Umemura T; Usami Y; Yamashita Y; Norman GL; Sugiura A; Yamazaki T; Fujimori N; Kimura T; Matsumoto A; Igarashi K; Yoshizawa K; Ota M; Tanaka E
  • Sci Rep 2018[]; 8 (ä): ä PMID29802350show ga
  • Autotaxin (ATX) is a secreted enzyme metabolized by liver sinusoidal endothelial cells that has been associated with liver fibrosis. We evaluated serum ATX values in 128 treatment-naïve, histologically assessed primary biliary cholangitis (PBC) patients and 80 healthy controls for comparisons of clinical parameters in a case-control study. The median ATX concentrations in controls and PBC patients of Nakanuma?s stage I, II, III, and IV were 0.70, 0.80, 0.87, 1.03, and 1.70?mg/L, respectively, which increased significantly with disease stage (r?=?0.53, P?
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