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10.1002/cphy.c150009 http://scihub22266oqcxt.onion/10.1002/cphy.c150009 C5965260!5965260!26756638     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Compr+Physiol 2015 ; 6 (1): 423-41 Nephropedia Template TP {{tp|p=26756638|t=2015. Cytochrome P450 and Lipoxygenase Metabolites on Renal Function |pdf=|usr=}}{{26756638}} gab.com Text Cytochrome P450 and Lipoxygenase Metabolites on Renal Function JO: Compr Physiol http://www.kidney.de/pget.php?&tw=1&pmid=26756638 #FOAvip Arachidonic acid metabolites have a myriad of biological actions including effects on the kidney to alter renal hemodynamics and tubular transport processes. Cyclooxygenase metabolites are products of an arachidonic acid enzymatic pathway that has been extensively studied in regards to renal function. Two lesser-known enzymatic pathways of arachidonic acid metabolism are the lipoxygenase (LO) and cytochrome P450 (CYP) pathways. The importance of LO and CYP metabolites to renal hemodynamics and tubular transport processes is now being recognized. LO and CYP metabolites have actions to alter renal blood flow and glomerular filtration rate. Proximal and distal tubular sodium transport and fluid and electrolyte homeostasis are also significantly influenced by renal CYP and LO levels. Metabolites of the LO and CYP pathways also have renal actions that influence renal inflammation, proliferation, and apoptotic processes at vascular and epithelial cells. These renal LO and CYP pathway actions occur through generation of specific metabolites and cell-signaling mechanisms. Even though the renal physiological importance and actions for LO and CYP metabolites are readily apparent, major gaps remain in our understanding of these lipid mediators to renal function. Future studies will be needed to fill these major gaps regarding LO and CYP metabolites on renal function. Twit Text FOAVip Cytochrome P450 and Lipoxygenase Metabolites on Renal Function ????Compr Physiol http://www.kidney.de/pget.php?&tw=1&pmid=26756638 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26756638 #FOAvip English Wikipedia <ref>{{Cite pmid|26756638}}</ref> Cytochrome P450 and Lipoxygenase Metabolites on Renal Function #MMPMID26756638 Imig JD; Hye Khan MA Compr Physiol 2015[Dec]; 6 (1): 423-41 PMID26756638show ga Arachidonic acid metabolites have a myriad of biological actions including effects on the kidney to alter renal hemodynamics and tubular transport processes. Cyclooxygenase metabolites are products of an arachidonic acid enzymatic pathway that has been extensively studied in regards to renal function. Two lesser-known enzymatic pathways of arachidonic acid metabolism are the lipoxygenase (LO) and cytochrome P450 (CYP) pathways. The importance of LO and CYP metabolites to renal hemodynamics and tubular transport processes is now being recognized. LO and CYP metabolites have actions to alter renal blood flow and glomerular filtration rate. Proximal and distal tubular sodium transport and fluid and electrolyte homeostasis are also significantly influenced by renal CYP and LO levels. Metabolites of the LO and CYP pathways also have renal actions that influence renal inflammation, proliferation, and apoptotic processes at vascular and epithelial cells. These renal LO and CYP pathway actions occur through generation of specific metabolites and cell-signaling mechanisms. Even though the renal physiological importance and actions for LO and CYP metabolites are readily apparent, major gaps remain in our understanding of these lipid mediators to renal function. Future studies will be needed to fill these major gaps regarding LO and CYP metabolites on renal function. äCytochrome P450 and Lipoxygenase Metabolites on Renal Function (epmc).pdf DeepDyve Pubget Overpricing