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10.1128/mBio.02331-17

http://scihub22266oqcxt.onion/10.1128/mBio.02331-17
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C5964356!5964356!29789364
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suck abstract from ncbi


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pmid29789364      mBio 2018 ; 9 (3): ä
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  • Bacterial Quorum Sensing and Microbial Community Interactions #MMPMID29789364
  • Abisado RG; Benomar S; Klaus JR; Dandekar AA; Chandler JR
  • mBio 2018[May]; 9 (3): ä PMID29789364show ga
  • Many bacteria use a cell-cell communication system called quorum sensing to coordinate population density-dependent changes in behavior. Quorum sensing involves production of and response to diffusible or secreted signals, which can vary substantially across different types of bacteria. In many species, quorum sensing modulates virulence functions and is important for pathogenesis. Over the past half-century, there has been a significant accumulation of knowledge of the molecular mechanisms, signal structures, gene regulons, and behavioral responses associated with quorum-sensing systems in diverse bacteria. More recent studies have focused on understanding quorum sensing in the context of bacterial sociality. Studies of the role of quorum sensing in cooperative and competitive microbial interactions have revealed how quorum sensing coordinates interactions both within a species and between species. Such studies of quorum sensing as a social behavior have relied on the development of ?synthetic ecological? models that use nonclonal bacterial populations. In this review, we discuss some of these models and recent advances in understanding how microbes might interact with one another using quorum sensing. The knowledge gained from these lines of investigation has the potential to guide studies of microbial sociality in natural settings and the design of new medicines and therapies to treat bacterial infections.
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