How T cells go rogue in the absence of Roquins #MMPMID29799562
Akef A; Muljo SA
Noncoding RNA Investig 2018[Apr]; 2 (ä): ä PMID29799562show ga
Roquin-1 and Roquin-2 are RNA-binding proteins essential for modulating T cell activity. Indeed, Roquin dysfunction has been linked to autoimmunity in mice. Essig and colleagues (2017) determine their functions in Foxp3+ T regulatory cells and uncover novel mechanisms of Roquin-mediated regulation of its target mRNAs (1).