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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Cent+Asian+J+Glob+Health
2014 ; 3
(Suppl
): 222
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Pregnancy Outcomes Complicated by Preterm Premature Rupture of Membranes:
Retrospective Review of Cases in Three Institutions in Kazakhstan
#MMPMID29805914
Imankulova B
; Aimagambetova G
; Saiddildina L
; Ukybassova T
Cent Asian J Glob Health
2014[]; 3
(Suppl
): 222
PMID29805914
show ga
INTRODUCTION: Pre-term premature rupture of membranes (PPROM) is one of the
leading causes of perinatal morbidity and mortality. This complication is
diagnosed in 3% of pregnant women in Kazakhstan, and it is the leading cause of
pre-term deliveries. The aim of this study was to determine the outcomes of
pregnancies complicated by PPROM in gestation periods between 24 to 32 weeks
among three institutions in Kazakhstan. METHODS: This is descriptive analysis of
154 cases with PPROM observed between 24 to 32 weeks of gestation at Perinatal
Centers #2 and #3 and the National Research Center for Maternal and Child Health,
Astana, Kazakhstan. Cases were selected on the basis of retrospective chart
review where PPROM diagnosis occurred in 2013. Descriptive statistics were
utilized for data analysis. RESULTS: The most frequent complications associated
with PPROM were threat of miscarriage (13.6% of cases) and chronic placental
insufficiency (7.8%). The mean time between PPROM and onset of spontaneous labor
was 12.1 ± 2.3 days. Spontaneous labor within 3 days after PPROM started in
patients with an amniotic fluid index of 3.0 ± 0.2 cm. Complications experienced
by PPROM women during delivery and early postpartum period included: precipitous
labor (6.4%), weakness of labor activity (16.2%), atonic hemorrhage (1.2%), and
chorioamnionitis (3.2%). 37.6% of newborns in this study were admitted to the
Intensive Care Unit. Their health complications included pneumonia (7.7%),
conjunctivitis (1.3%), omphalitis and infectious-toxic shock (3.8%),
intraventricular hemorrhage (7.8%), and respiratory distress (10.3%). CONCLUSION:
Thus, preterm rupture of membranes is associated with preterm delivery and an
increase of neonatal morbidity. Therefore, it is necessary to find ways to
effectively manage PPROM, including developing new techniques to restore the
amniotic fluid volume in women experiencing PPROM during 24 to 32 weeks of
gestation.