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10.1038/s41598-018-26198-7 http://scihub22266oqcxt.onion/10.1038/s41598-018-26198-7 C5959865!5959865!29777149     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2018 ; 8 (ä): ä Nephropedia Template TP {{tp|p=29777149|t=2018. Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model |pdf=|usr=}}{{29777149}} gab.com Text Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29777149 #FOAvip There is growing interest in developing non-pharmacological treatments that could boost natural defenses against cancer and contribute to primary and secondary cancer prevention. Recent studies have shown that gentle daily stretching for 10?minutes can reduce local connective tissue inflammation and fibrosis. Because mechanical factors within the stroma can influence the tumor microenvironment, we hypothesized that stretching would reduce the growth of tumors implanted within locally stretched tissues and tested this hypothesis in a mouse orthotopic breast cancer model. Female FVB mice (N?=?66) underwent bilateral injection of p53/PTEN double-null primary mouse mammary tumor cells into the third mammary fat pad. Mice were randomized to stretch vs. no stretch, and treated for 10?minutes once a day, for four weeks. Tumor volume at end-point was 52% smaller in the stretch group, compared to the no-stretch group (p?<?0.001) in the absence of any other treatment. Cytotoxic immune responses were activated and levels of Specialized Pro-Resolving Mediators were elevated in the stretch group. These results suggest a link between immune exhaustion, inflammation resolution and tumor growth. Stretching is a gentle, non-pharmacological intervention that could become an important component of cancer treatment and prevention. Twit Text FOAVip Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=29777149 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29777149 #FOAvip English Wikipedia <ref>{{Cite pmid|29777149}}</ref> Stretching Reduces Tumor Growth in a Mouse Breast Cancer Model #MMPMID29777149 Berrueta L; Bergholz J; Munoz D; Muskaj I; Badger GJ; Shukla A; Kim HJ; Zhao JJ; Langevin HM Sci Rep 2018[]; 8 (ä): ä PMID29777149show ga There is growing interest in developing non-pharmacological treatments that could boost natural defenses against cancer and contribute to primary and secondary cancer prevention. Recent studies have shown that gentle daily stretching for 10?minutes can reduce local connective tissue inflammation and fibrosis. Because mechanical factors within the stroma can influence the tumor microenvironment, we hypothesized that stretching would reduce the growth of tumors implanted within locally stretched tissues and tested this hypothesis in a mouse orthotopic breast cancer model. Female FVB mice (N?=?66) underwent bilateral injection of p53/PTEN double-null primary mouse mammary tumor cells into the third mammary fat pad. Mice were randomized to stretch vs. no stretch, and treated for 10?minutes once a day, for four weeks. Tumor volume at end-point was 52% smaller in the stretch group, compared to the no-stretch group (p? äStretching Reduces Tumor Growth in a Mouse Breast Cancer Model (epmc).pdf DeepDyve Pubget Overpricing