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10.1038/s41598-018-26142-9

http://scihub22266oqcxt.onion/10.1038/s41598-018-26142-9
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C5958068!5958068!29773914
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suck abstract from ncbi


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pmid29773914      Sci+Rep 2018 ; 8 (ä): ä
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  • Risk factors for severe hypocalcemia after parathyroidectomy in dialysis patients with secondary hyperparathyroidism #MMPMID29773914
  • Sun X; Zhang X; Lu Y; Zhang L; Yang M
  • Sci Rep 2018[]; 8 (ä): ä PMID29773914show ga
  • Severe hypocalcemia (SH) is a common and serious complication in dialysis patients with secondary hyperparathyroidism (SHPT) after parathyroidectomy (PTX). The aim is to explore the risk predictors of SH in post-PTX dialysis ESRD patients with SHPT. 129 consecutive dialysis patients with SHPT underwent PTX were retrospectively reviewed. A total of 22 clinical parameters were included in the study. SH was defined as the minimum values of serum calcium lower than 1.875?mmol/L (7.5?mg/dL) after surgery. Univariate analysis showed that pruritus, lumbar X-ray changes of renal osteodystrophy, pre- and post-operative intact parathyroid hormone (iPTH), Calcium, alkaline phosphatase, and gland mass were significantly different between SH and non-SH groups. In the multivariate logistic regression model, the pre-operative serum iPTH, calcium, and pruritus were independent risk predictors of SH. AUCs for pre-operative serum iPTH, calcium and pruritus were 0.810, 0.714 and 0.591, respectively. Patients with higher level of pre-operative serum iPTH, lower level of serum calcium and with no/mild symptoms of pruritus are at greater risk of developing SH after PTX.
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