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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Environ+Health+Prev+Med 2018 ; 23 (ä): ä Nephropedia Template TP
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The toxicological mechanisms and detoxification of depleted uranium exposure #MMPMID29769021
Yue YC; Li MH; Wang HB; Zhang BL; He W
Environ Health Prev Med 2018[]; 23 (ä): ä PMID29769021show ga
Depleted uranium (DU) has been widely applied in industrial and military activities, and is often obtained from producing fuel for nuclear reactors. DU may be released into the environment, polluting air, soil, and water, and is considered to exert both radiological and chemical toxicity. In humans and animals, DU can induce multiple health effects, such as renal tubular necrosis and bone malignancies. This review summarizes the known information on DU?s routes of entry, mechanisms of toxicity, and health effects. In addition, we survey the chelating agents used in ameliorating DU toxicity.