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10.1007/s00294-017-0793-5 http://scihub22266oqcxt.onion/10.1007/s00294-017-0793-5 C5948300!5948300!29218463     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Genet 2018 ; 64 (3): 581-8 Nephropedia Template TP {{tp|p=29218463|t=2018. One-two punch mechanism of gene repression: a fresh perspective on gene regulation |pdf=|usr=}}{{29218463}} gab.com Text One-two punch mechanism of gene repression: a fresh perspective on gene regulation JO: Curr Genet http://www.kidney.de/pget.php?&tw=1&pmid=29218463 #FOAvip Cellular differentiation depends on temporally controlled waves of gene activation and inactivation that ultimately transform one cell type into another. It is well established that transcription factor cascades coordinate the timely activation of gene expression clusters during development. In comparison, much less is understood about how gene repression events are coordinated with the transcription factor-driven waves of gene activation and how this repression is achieved at a mechanistic level. Using budding yeast as a model, we recently discovered a new gene regulatory event, whereby a central meiotic transcription factor induces the expression of an mRNA isoform to repress gene expression through an integrated transcriptional and translational mechanism. This new model could explain how gene activation and inactivation waves can be temporally coordinated. In this review, we discuss our findings and their potential implications. Twit Text FOAVip One-two punch mechanism of gene repression: a fresh perspective on gene regulation ????Curr Genet http://www.kidney.de/pget.php?&tw=1&pmid=29218463 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29218463 #FOAvip English Wikipedia <ref>{{Cite pmid|29218463}}</ref> One-two punch mechanism of gene repression: a fresh perspective on gene regulation #MMPMID29218463 Tresenrider A; Ünal E Curr Genet 2018[]; 64 (3): 581-8 PMID29218463show ga Cellular differentiation depends on temporally controlled waves of gene activation and inactivation that ultimately transform one cell type into another. It is well established that transcription factor cascades coordinate the timely activation of gene expression clusters during development. In comparison, much less is understood about how gene repression events are coordinated with the transcription factor-driven waves of gene activation and how this repression is achieved at a mechanistic level. Using budding yeast as a model, we recently discovered a new gene regulatory event, whereby a central meiotic transcription factor induces the expression of an mRNA isoform to repress gene expression through an integrated transcriptional and translational mechanism. This new model could explain how gene activation and inactivation waves can be temporally coordinated. In this review, we discuss our findings and their potential implications. äOne-two punch mechanism of gene repression: a fresh perspective on gen(epmc).pdf DeepDyve Pubget Overpricing