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Subungual Amelanotic Melanoma Masquerading as Onychomycosis #MMPMID29755903
Riahi RR; Cohen PR; Goldberg LH
Cureus ä[]; 10 (3): ä PMID29755903show ga
Subungual amelanotic melanoma is rare. In addition, amelanotic melanoma can mimic non-melanocytic tumors. A 67-year-old woman had a four-year history of dystrophy of the left fourth fingernail. Periodic acid-Schiff staining of the nail plate demonstrated fungal hyphae, establishing a diagnosis of tinea unguium. The nail plate subsequently detached and the underlying nail bed showed a red, friable mass that was biopsied and confirmed a diagnosis of melanoma. In conclusion, additional morphologic change of a persistent nail dystrophy?even with a biopsy-confirmed diagnosis of onychomycosis?may require consideration for repeat evaluation, including a biopsy, to exclude the possibility of a subungual malignant tumor.