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10.1111/1346-8138.14231 http://scihub22266oqcxt.onion/10.1111/1346-8138.14231 C5947617!5947617 !29356076     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29356076 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Dermatol 2018 ; 45 (5 ): 580-583 Nephropedia Template TP {{tp|p=29356076 |t=2018. Successful management of steroid-resistant vascular tumors associated with the Kasabach-Merritt phenomenon using sirolimus |pdf=|usr=}}{{29356076 }} gab.com Text Successful management of steroid-resistant vascular tumors associated with the Kasabach-Merritt phenomenon using sirolimus JO: J Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=29356076 #FOAvip Vascular tumors associated with Kasabach-Merritt phenomenon (KMP) are life-threatening and the mortality is as high as 10-30%. Steroids are considered the primary choice for drug therapy. However, there are many steroid-resistant cases. In the present study, analyzed data are presented to support the use of sirolimus in clinical practise for the treatment of corticosteroid-resistant vascular tumors with KMP in eight infants between June 2015 and April 2017 in a single hospital. The time to initial response was 6.8 ± 2.7 days. The average stabilization time for the platelet count was 19.1 ± 8.5 days. At the time of publication, the average duration of sirolimus treatment was 14.1 ± 4.0 months, and the average time for sirolimus treatment as a single agent was 12.6 ± 4.2 months. The side-effects were tolerable and included oral ulcer, fever, pain, skin rash and transient ascension of serum transaminase and cholesterol. Our study indicated that sirolimus therapy is an effective and safe method for the treatment of corticosteroid resistant vascular tumors associated with KMP in infants. Twit Text FOAVip Successful management of steroid-resistant vascular tumors associated with the Kasabach-Merritt phenomenon using sirolimus ????J Dermatol http://www.kidney.de/pget.php?&tw=1&pmid=29356076 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29356076 #FOAvip English Wikipedia <ref>{{Cite pmid|29356076 }}</ref> Successful management of steroid-resistant vascular tumors associated with the Kasabach-Merritt phenomenon using sirolimus #MMPMID29356076 Tan X ; Zhang J ; Zhou S ; Liu Z ; Zhang T ; Xia J J Dermatol 2018[May]; 45 (5 ): 580-583 PMID29356076 show ga Vascular tumors associated with Kasabach-Merritt phenomenon (KMP) are life-threatening and the mortality is as high as 10-30%. Steroids are considered the primary choice for drug therapy. However, there are many steroid-resistant cases. In the present study, analyzed data are presented to support the use of sirolimus in clinical practise for the treatment of corticosteroid-resistant vascular tumors with KMP in eight infants between June 2015 and April 2017 in a single hospital. The time to initial response was 6.8 ± 2.7 days. The average stabilization time for the platelet count was 19.1 ± 8.5 days. At the time of publication, the average duration of sirolimus treatment was 14.1 ± 4.0 months, and the average time for sirolimus treatment as a single agent was 12.6 ± 4.2 months. The side-effects were tolerable and included oral ulcer, fever, pain, skin rash and transient ascension of serum transaminase and cholesterol. Our study indicated that sirolimus therapy is an effective and safe method for the treatment of corticosteroid resistant vascular tumors associated with KMP in infants. |*Drug Resistance, Neoplasm [MESH] |Antibiotics, Antineoplastic/*therapeutic use [MESH] |Biopsy [MESH] |Female [MESH] |Glucocorticoids/*pharmacology/therapeutic use [MESH] |Humans [MESH] |Infant [MESH] |Kasabach-Merritt Syndrome/blood/complications/*drug therapy/pathology [MESH] |Magnetic Resonance Imaging [MESH] |Male [MESH] |Platelet Count [MESH] |Response Evaluation Criteria in Solid Tumors [MESH] |Retrospective Studies [MESH] |Sirolimus/*therapeutic use [MESH] |Time Factors [MESH]Successful management of steroid-resistant vascular tumors associated (epmc).pdf DeepDyve Pubget Overpricing