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10.1111/cea.13117 http://scihub22266oqcxt.onion/10.1111/cea.13117 C5947573!5947573!29431885     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Exp+Allergy 2018 ; 48 (5): 502-12 Nephropedia Template TP {{tp|p=29431885|t=2018. Important and specific role for basophils in acute allergic reactions |pdf=|usr=}}{{29431885}} gab.com Text Important and specific role for basophils in acute allergic reactions JO: Clin Exp Allergy http://www.kidney.de/pget.php?&tw=1&pmid=29431885 #FOAvip IgE?mediated allergic reactions involve the activation of effector cells, predominantly through the high?affinity IgE receptor (Fc?RI) on mast cells and basophils. Although the mast cell is considered the major effector cell during acute allergic reactions, more recent studies indicate a potentially important and specific role for basophils and their migration which occurs rapidly upon allergen challenge in humans undergoing anaphylaxis. We review the evidence for a role of basophils in contributing to clinical symptoms of anaphylaxis and discuss the possibility that basophil trafficking during anaphylaxis might be a pathogenic (to target organs) or protective (preventing degranulation in circulation) response. Finally, we examine the potential role of basophils in asthma exacerbations. Understanding the factors that regulate basophil trafficking and activation might lead to new diagnostic and therapeutic strategies in anaphylaxis and asthma. Twit Text FOAVip Important and specific role for basophils in acute allergic reactions ????Clin Exp Allergy http://www.kidney.de/pget.php?&tw=1&pmid=29431885 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29431885 #FOAvip English Wikipedia <ref>{{Cite pmid|29431885}}</ref> Important and specific role for basophils in acute allergic reactions #MMPMID29431885 Koro?ec P; Gibbs BF; Rijavec M; Custovic A; Turner PJ Clin Exp Allergy 2018[May]; 48 (5): 502-12 PMID29431885show ga IgE?mediated allergic reactions involve the activation of effector cells, predominantly through the high?affinity IgE receptor (Fc?RI) on mast cells and basophils. Although the mast cell is considered the major effector cell during acute allergic reactions, more recent studies indicate a potentially important and specific role for basophils and their migration which occurs rapidly upon allergen challenge in humans undergoing anaphylaxis. We review the evidence for a role of basophils in contributing to clinical symptoms of anaphylaxis and discuss the possibility that basophil trafficking during anaphylaxis might be a pathogenic (to target organs) or protective (preventing degranulation in circulation) response. Finally, we examine the potential role of basophils in asthma exacerbations. Understanding the factors that regulate basophil trafficking and activation might lead to new diagnostic and therapeutic strategies in anaphylaxis and asthma. äImportant and specific role for basophils in acute allergic reactions (epmc).pdf DeepDyve Pubget Overpricing