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10.1002/iid3.223 http://scihub22266oqcxt.onion/10.1002/iid3.223 C5946157!5946157!29635889     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immun+Inflamm+Dis 2018 ; 6 (2): 354-70 Nephropedia Template TP {{tp|p=29635889|t=2018. Neural architecture in lymphoid organs: Hard?wired antigen presenting cells and neurite networks in antigen entrance areas |pdf=|usr=}}{{29635889}} gab.com Text Neural architecture in lymphoid organs: Hard wired antigen presenting cells and neurite networks in antigen entrance areas JO: Immun Inflamm Dis http://www.kidney.de/pget.php?&tw=1&pmid=29635889 #FOAvip Introduction: Recently, we found abundant innervation of antigen presenting cells that were reached and enclosed by single neurites. These neurally hard?wired antigen presenting cells (wAPC) could be observed in the T?cell zone of superficial cervical lymph nodes of rats and other mammalians, including humans. Methods: As a consequence, we investigated lymph nodes at many different anatomical positions as well as all primary and secondary lymphoid organs (SLO) in rodents for a similar morphology of innervation regarding antigen presenting cells known in those tissues. Results: As a result, we confirmed wAPC in lymph nodes independent from their draining areas and anatomical positions but also in all other T?cell zones of lymphoid organs, like Peyer's patches, NALT and BALT, as well as in the thymic medulla. Other cells were innervated in a similar fashion but with seemingly missing antigen presenting capacity. Both types of innervated immune cells were observed as being also present in the dermis of the skin. Only in the spleen wAPC could not be detected. Beyond this systematic finding, we also found another regular phenomenon: a dense network of neurites that stained for neurofilament always in antigen entrance areas of lymphoid organs (subsinoidal layer of lymph nodes, subepithelial dome of Peyer's patches, subsinoidal layer of the splenic white pulp, margins of NALT and BALT). Lastly, also thymic epithelial cells (TEC) restricted to the corticomedullary junction of the thymus showed similar neurofilament staining. Conclusions: Therefore, we propose much more hard?wired and probably afferent connections between lymphoid organs and the central nervous system than is hitherto known. Twit Text FOAVip Neural architecture in lymphoid organs: Hard wired antigen presenting cells and neurite networks in antigen entrance areas ????Immun Inflamm Dis http://www.kidney.de/pget.php?&tw=1&pmid=29635889 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29635889 #FOAvip English Wikipedia <ref>{{Cite pmid|29635889}}</ref> Neural architecture in lymphoid organs: Hard?wired antigen presenting cells and neurite networks in antigen entrance areas #MMPMID29635889 Wülfing C; Schuran FA; Urban J; Oehlmann J; Günther HS Immun Inflamm Dis 2018[Jun]; 6 (2): 354-70 PMID29635889show ga Introduction: Recently, we found abundant innervation of antigen presenting cells that were reached and enclosed by single neurites. These neurally hard?wired antigen presenting cells (wAPC) could be observed in the T?cell zone of superficial cervical lymph nodes of rats and other mammalians, including humans. Methods: As a consequence, we investigated lymph nodes at many different anatomical positions as well as all primary and secondary lymphoid organs (SLO) in rodents for a similar morphology of innervation regarding antigen presenting cells known in those tissues. Results: As a result, we confirmed wAPC in lymph nodes independent from their draining areas and anatomical positions but also in all other T?cell zones of lymphoid organs, like Peyer's patches, NALT and BALT, as well as in the thymic medulla. Other cells were innervated in a similar fashion but with seemingly missing antigen presenting capacity. Both types of innervated immune cells were observed as being also present in the dermis of the skin. Only in the spleen wAPC could not be detected. Beyond this systematic finding, we also found another regular phenomenon: a dense network of neurites that stained for neurofilament always in antigen entrance areas of lymphoid organs (subsinoidal layer of lymph nodes, subepithelial dome of Peyer's patches, subsinoidal layer of the splenic white pulp, margins of NALT and BALT). Lastly, also thymic epithelial cells (TEC) restricted to the corticomedullary junction of the thymus showed similar neurofilament staining. Conclusions: Therefore, we propose much more hard?wired and probably afferent connections between lymphoid organs and the central nervous system than is hitherto known. äNeural architecture in lymphoid organs: Hard?wired antigen presenting (epmc).pdf DeepDyve Pubget Overpricing