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10.5811/westjem.2018.1.36891

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suck abstract from ncbi


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pmid29760840
      West+J+Emerg+Med 2018 ; 19 (3 ): 460-464
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  • Clinical Ultrasound Is Safe and Highly Specific for Acute Appendicitis in Moderate to High Pre-test Probability Patients #MMPMID29760840
  • Corson-Knowles D ; Russell FM
  • West J Emerg Med 2018[May]; 19 (3 ): 460-464 PMID29760840 show ga
  • INTRODUCTION: Clinical ultrasound (CUS) is highly specific for the diagnosis of acute appendicitis but is operator-dependent. The goal of this study was to determine if a heterogeneous group of emergency physicians (EP) could diagnose acute appendicitis on CUS in patients with a moderate to high pre-test probability. METHODS: This was a prospective, observational study of a convenience sample of adult and pediatric patients with suspected appendicitis. Sonographers received a structured, 20-minute CUS training on appendicitis prior to patient enrollment. The presence of a dilated (>6 mm diameter), non-compressible, blind-ending tubular structure was considered a positive study. Non-visualization or indeterminate studies were considered negative. We collected pre-test probability of acute appendicitis based on a 10-point visual analog scale (moderate to high was defined as >3), and confidence in CUS interpretation. The primary objective was measured by comparing CUS findings to surgical pathology and one week follow-up. RESULTS: We enrolled 105 patients; 76 had moderate to high pre-test probability. Of these, 24 were children. The rate of appendicitis was 36.8% in those with moderate to high pre-test probability. CUS were recorded by 33 different EPs. The sensitivity, specificity, and positive and negative likelihood ratios of EP-performed CUS in patients with moderate to high pre-test probability were 42.8% (95% confidence interval [CI] [25-62.5%]), 97.9% (95% CI [87.5-99.8%]), 20.7 (95% CI [2.8-149.9]) and 0.58 (95% CI [0.42-0.8]), respectively. The 16 false negative scans were all interpreted as indeterminate. There was one false positive CUS diagnosis; however, the sonographer reported low confidence of 2/10. CONCLUSION: A heterogeneous group of EP sonographers can safely identify acute appendicitis with high specificity in patients with moderate to high pre-test probability. This data adds support for surgical consultation without further imaging beyond CUS in the appropriate clinical setting.
  • |*Acute Disease [MESH]
  • |*Visual Analog Scale [MESH]
  • |Adolescent [MESH]
  • |Appendicitis/*diagnosis [MESH]
  • |Emergency Medicine [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Pain Measurement [MESH]
  • |Physicians/standards [MESH]
  • |Probability [MESH]
  • |Prospective Studies [MESH]
  • |Sensitivity and Specificity [MESH]
  • |Ultrasonography/instrumentation/*methods [MESH]
  • |Workforce [MESH]


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