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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 West+J+Emerg+Med
2018 ; 19
(3
): 460-464
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Clinical Ultrasound Is Safe and Highly Specific for Acute Appendicitis in
Moderate to High Pre-test Probability Patients
#MMPMID29760840
Corson-Knowles D
; Russell FM
West J Emerg Med
2018[May]; 19
(3
): 460-464
PMID29760840
show ga
INTRODUCTION: Clinical ultrasound (CUS) is highly specific for the diagnosis of
acute appendicitis but is operator-dependent. The goal of this study was to
determine if a heterogeneous group of emergency physicians (EP) could diagnose
acute appendicitis on CUS in patients with a moderate to high pre-test
probability. METHODS: This was a prospective, observational study of a
convenience sample of adult and pediatric patients with suspected appendicitis.
Sonographers received a structured, 20-minute CUS training on appendicitis prior
to patient enrollment. The presence of a dilated (>6 mm diameter),
non-compressible, blind-ending tubular structure was considered a positive study.
Non-visualization or indeterminate studies were considered negative. We collected
pre-test probability of acute appendicitis based on a 10-point visual analog
scale (moderate to high was defined as >3), and confidence in CUS interpretation.
The primary objective was measured by comparing CUS findings to surgical
pathology and one week follow-up. RESULTS: We enrolled 105 patients; 76 had
moderate to high pre-test probability. Of these, 24 were children. The rate of
appendicitis was 36.8% in those with moderate to high pre-test probability. CUS
were recorded by 33 different EPs. The sensitivity, specificity, and positive and
negative likelihood ratios of EP-performed CUS in patients with moderate to high
pre-test probability were 42.8% (95% confidence interval [CI] [25-62.5%]), 97.9%
(95% CI [87.5-99.8%]), 20.7 (95% CI [2.8-149.9]) and 0.58 (95% CI [0.42-0.8]),
respectively. The 16 false negative scans were all interpreted as indeterminate.
There was one false positive CUS diagnosis; however, the sonographer reported low
confidence of 2/10. CONCLUSION: A heterogeneous group of EP sonographers can
safely identify acute appendicitis with high specificity in patients with
moderate to high pre-test probability. This data adds support for surgical
consultation without further imaging beyond CUS in the appropriate clinical
setting.