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10.2217/fca-2016-0059 http://scihub22266oqcxt.onion/10.2217/fca-2016-0059 C5941715!5941715!28581332     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Future+Cardiol 2017 ; 13 (3): 259-78 Nephropedia Template TP {{tp|p=28581332|t=2017. PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR-? |pdf=|usr=}}{{28581332}} gab.com Text PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR- JO: Future Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28581332 #FOAvip This article provides a comprehensive review about the molecular and metabolic actions of PPAR-?. It describes its structural features, ligand specificity, gene transcription mechanisms, functional characteristics and target genes. In addition, recent progress with the use of loss of function and gain of function mouse models in the discovery of diverse biological functions of PPAR-?, particularly in the vascular system and the status of the development of new single, dual, pan and partial PPAR agonists (PPAR modulators) in the clinical management of metabolic diseases are presented. This review also summarizes the clinical outcomes from a large number of clinical trials aimed at evaluating the atheroprotective actions of current clinically used PPAR-? agonists, fibrates and statin?fibrate combination therapy. Twit Text FOAVip PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR- ????Future Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28581332 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28581332 #FOAvip English Wikipedia <ref>{{Cite pmid|28581332}}</ref> PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR-? #MMPMID28581332 Han L; Shen WJ; Bittner S; Kraemer FB; Azhar S Future Cardiol 2017[May]; 13 (3): 259-78 PMID28581332show ga This article provides a comprehensive review about the molecular and metabolic actions of PPAR-?. It describes its structural features, ligand specificity, gene transcription mechanisms, functional characteristics and target genes. In addition, recent progress with the use of loss of function and gain of function mouse models in the discovery of diverse biological functions of PPAR-?, particularly in the vascular system and the status of the development of new single, dual, pan and partial PPAR agonists (PPAR modulators) in the clinical management of metabolic diseases are presented. This review also summarizes the clinical outcomes from a large number of clinical trials aimed at evaluating the atheroprotective actions of current clinically used PPAR-? agonists, fibrates and statin?fibrate combination therapy. äPPARs: regulators of metabolism and as therapeutic targets in cardiova(epmc).pdf DeepDyve Pubget Overpricing