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10.2217/fca-2016-0059 http://scihub22266oqcxt.onion/10.2217/fca-2016-0059 C5941715!5941715 !28581332     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28581332 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28581332 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Future+Cardiol 2017 ; 13 (3 ): 259-278 Nephropedia Template TP {{tp|p=28581332 |t=2017. PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR-? |pdf=|usr=}}{{28581332 }} gab.com Text PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR- JO: Future Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28581332 #FOAvip This article provides a comprehensive review about the molecular and metabolic actions of PPAR-?. It describes its structural features, ligand specificity, gene transcription mechanisms, functional characteristics and target genes. In addition, recent progress with the use of loss of function and gain of function mouse models in the discovery of diverse biological functions of PPAR-?, particularly in the vascular system and the status of the development of new single, dual, pan and partial PPAR agonists (PPAR modulators) in the clinical management of metabolic diseases are presented. This review also summarizes the clinical outcomes from a large number of clinical trials aimed at evaluating the atheroprotective actions of current clinically used PPAR-? agonists, fibrates and statin-fibrate combination therapy. Twit Text FOAVip PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR- ????Future Cardiol http://www.kidney.de/pget.php?&tw=1&pmid=28581332 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28581332 #FOAvip English Wikipedia <ref>{{Cite pmid|28581332 }}</ref> PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease Part I: PPAR-? #MMPMID28581332 Han L ; Shen WJ ; Bittner S ; Kraemer FB ; Azhar S Future Cardiol 2017[May]; 13 (3 ): 259-278 PMID28581332 show ga This article provides a comprehensive review about the molecular and metabolic actions of PPAR-?. It describes its structural features, ligand specificity, gene transcription mechanisms, functional characteristics and target genes. In addition, recent progress with the use of loss of function and gain of function mouse models in the discovery of diverse biological functions of PPAR-?, particularly in the vascular system and the status of the development of new single, dual, pan and partial PPAR agonists (PPAR modulators) in the clinical management of metabolic diseases are presented. This review also summarizes the clinical outcomes from a large number of clinical trials aimed at evaluating the atheroprotective actions of current clinically used PPAR-? agonists, fibrates and statin-fibrate combination therapy. |Animals [MESH] |Cardiovascular Diseases/*drug therapy/prevention & control [MESH] |Clinical Trials as Topic [MESH] |Humans [MESH] |Mice [MESH]PPARs: regulators of metabolism and as therapeutic targets in cardiova(epmc).pdf DeepDyve Pubget Overpricing