Ezh2 Lines Up the Chromatin in T Regulatory Cells #MMPMID25692693
Wu C; Chen Z; Kuchroo VK
Immunity 2015[Feb]; 42 (2): 201-3 PMID25692693show ga
Epigenetic modulation is critical for regulating the development and function of T cells. In this issue of Immunity, DuPage et al. (2015) show that the chromatin-modifying enzyme Ezh2 induced by CD28 costimulation is essential for regulatory T (Treg) cell maintenance during activation and differentiation.