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10.18632/oncotarget.25130 http://scihub22266oqcxt.onion/10.18632/oncotarget.25130 C5940372!5940372 !29765552     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29765552 &cmd=llinks): Failed to open stream: HTTP request failed! 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Higher enterococcus counts indicate a lower risk of colorectal adenomas: a prospective cohort study |pdf=|usr=}}{{29765552 }} gab.com Text Higher enterococcus counts indicate a lower risk of colorectal adenomas: a prospective cohort study JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29765552 #FOAvip Intestinal bacteria play an important role in human health. This prospective cohort study aimed to investigate the relationship between the abundance of different intestinal bacteria and the risk of developing colorectal cancer (CRC). Fecal samples from CRC patients (n = 157) were collected at the start of the study wherein patients subsequently underwent endoscopy to remove polyps. Gut bacteria were isolated by using specific culture methods and the fecal counts of various bacteria were quantified by reverse-transcription-quantitative-PCR (RT-qPCR) assays. The obtained data were subjected to cohort analysis in relation to the incidence of colorectal adenomas after 4 years of intervention. No relationship was detected between the counts of major intestinal bacteria and the incidence of colorectal adenomas. However, interestingly, a significant negative correlation was noted between colorectal adenoma incidence and the counts of bacteria grown on Columbia blood agar base (COBA) (P = 0.007). The risk ratio of colorectal adenomas was 0.58 (95% CI: 0.35-0.96) in the group with the highest bacterial count compared to the lowest. Bacteria grown on COBA were more abundant in older patients, non-smoking patients, and patients with a lower body mass index. The RT-qPCR results revealed a significantly lower colorectal adenoma incidence in subjects with higher enterococcal count as compared to subjects with a lower count, with a risk ratio of 0.47 (95% CI: 0.30-0.76). Correlation of a higher enterococci count with a lower risk of CRC development suggests that certain Enterococcus strains may have adenoma suppressive effects. Twit Text FOAVip Higher enterococcus counts indicate a lower risk of colorectal adenomas: a prospective cohort study ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29765552 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29765552 #FOAvip English Wikipedia <ref>{{Cite pmid|29765552 }}</ref> Higher enterococcus counts indicate a lower risk of colorectal adenomas: a prospective cohort study #MMPMID29765552 Kawano A ; Ishikawa H ; Mutoh M ; Kubota H ; Matsuda K ; Tsuji H ; Matsumoto K ; Nomoto K ; Tanaka R ; Nakamura T ; Wakabayashi K ; Sakai T Oncotarget 2018[Apr]; 9 (30 ): 21459-21467 PMID29765552 show ga Intestinal bacteria play an important role in human health. This prospective cohort study aimed to investigate the relationship between the abundance of different intestinal bacteria and the risk of developing colorectal cancer (CRC). Fecal samples from CRC patients (n = 157) were collected at the start of the study wherein patients subsequently underwent endoscopy to remove polyps. Gut bacteria were isolated by using specific culture methods and the fecal counts of various bacteria were quantified by reverse-transcription-quantitative-PCR (RT-qPCR) assays. The obtained data were subjected to cohort analysis in relation to the incidence of colorectal adenomas after 4 years of intervention. No relationship was detected between the counts of major intestinal bacteria and the incidence of colorectal adenomas. However, interestingly, a significant negative correlation was noted between colorectal adenoma incidence and the counts of bacteria grown on Columbia blood agar base (COBA) (P = 0.007). The risk ratio of colorectal adenomas was 0.58 (95% CI: 0.35-0.96) in the group with the highest bacterial count compared to the lowest. Bacteria grown on COBA were more abundant in older patients, non-smoking patients, and patients with a lower body mass index. The RT-qPCR results revealed a significantly lower colorectal adenoma incidence in subjects with higher enterococcal count as compared to subjects with a lower count, with a risk ratio of 0.47 (95% CI: 0.30-0.76). Correlation of a higher enterococci count with a lower risk of CRC development suggests that certain Enterococcus strains may have adenoma suppressive effects. äHigher enterococcus counts indicate a lower risk of colorectal adenoma(epmc).pdf DeepDyve Pubget Overpricing