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10.1083/jcb.201708023

http://scihub22266oqcxt.onion/10.1083/jcb.201708023
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C5940300!5940300!29599208
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suck abstract from ncbi


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pmid29599208      J+Cell+Biol 2018 ; 217 (5): 1667-85
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  • Lgr5+ intestinal stem cells reside in an unlicensed G1 phase #MMPMID29599208
  • Carroll TD; Newton IP; Chen Y; Blow JJ; Näthke I
  • J Cell Biol 2018[May]; 217 (5): 1667-85 PMID29599208show ga
  • Cell cycles of intestinal stem and transit-amplifying cells are poorly understood. Comparing total and DNA-bound Mcm2 in intact intestinal crypts, Carroll et al. show that most stem cells reside for long periods in the unlicensed G1 phase. In the unlicensed G1 phase, stem cells could interpret cues before resuming cell division.
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