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10.4081/oncol.2018.348 http://scihub22266oqcxt.onion/10.4081/oncol.2018.348 C5939831!5939831!29774136     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncol+Rev 2018 ; 12 (1): ä Nephropedia Template TP {{tp|p=29774136|t=2018. The impact of Mir-9 regulation in normal and malignant hematopoiesis |pdf=|usr=}}{{29774136}} gab.com Text The impact of Mir-9 regulation in normal and malignant hematopoiesis JO: Oncol Rev http://www.kidney.de/pget.php?&tw=1&pmid=29774136 #FOAvip MicroRNA-9 (MiR-9) dysregulation has been observed in various cancers. Recently, MiR-9 is considered to have a part in hematopoiesis and hematologic malignancies. However, its importance in blood neoplasms is not yet well defined. Thus, this study was conducted in order to assess the significance of MiR-9 role in the development of hematologic neoplasia, prognosis, and treatment approaches. We have shown that a large number of MiR-9 targets (such as FOXOs, SIRT1, CCND1, ID2, CCNG1, Ets, and NFkB) play essential roles in leukemogenesis and that it is overexpressed in different leukemias. Our findings indicated MiR-9 downregulation in a majority of leukemias. However, its overexpression was reported in patients with dysregulated MiR-9 controlling factors (such as MLLr). Additionally, prognostic value of MiR-9 has been reported in some types of leukemia. This study generally emphasizes on the critical role of MiR-9 in hematologic malignancies as a prognostic factor and a therapeutic target. Twit Text FOAVip The impact of Mir-9 regulation in normal and malignant hematopoiesis ????Oncol Rev http://www.kidney.de/pget.php?&tw=1&pmid=29774136 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29774136 #FOAvip English Wikipedia <ref>{{Cite pmid|29774136}}</ref> The impact of Mir-9 regulation in normal and malignant hematopoiesis #MMPMID29774136 Khosravi A; Alizadeh S; Jalili A; Shirzad R; Saki N Oncol Rev 2018[Jan]; 12 (1): ä PMID29774136show ga MicroRNA-9 (MiR-9) dysregulation has been observed in various cancers. Recently, MiR-9 is considered to have a part in hematopoiesis and hematologic malignancies. However, its importance in blood neoplasms is not yet well defined. Thus, this study was conducted in order to assess the significance of MiR-9 role in the development of hematologic neoplasia, prognosis, and treatment approaches. We have shown that a large number of MiR-9 targets (such as FOXOs, SIRT1, CCND1, ID2, CCNG1, Ets, and NFkB) play essential roles in leukemogenesis and that it is overexpressed in different leukemias. Our findings indicated MiR-9 downregulation in a majority of leukemias. However, its overexpression was reported in patients with dysregulated MiR-9 controlling factors (such as MLLr). Additionally, prognostic value of MiR-9 has been reported in some types of leukemia. This study generally emphasizes on the critical role of MiR-9 in hematologic malignancies as a prognostic factor and a therapeutic target. äThe impact of Mir-9 regulation in normal and malignant hematopoiesis (epmc).pdf DeepDyve Pubget Overpricing