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10.2217/fvl-2017-0106

http://scihub22266oqcxt.onion/10.2217/fvl-2017-0106
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C5939598!5939598!29750084
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suck abstract from ncbi

pmid29750084      Future+Virol 2018 ; 13 (3): 211-23
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  • Viral manipulation of host mRNA decay #MMPMID29750084
  • Guo L; Vlasova-St Louis I; Bohjanen PR
  • Future Virol 2018[Mar]; 13 (3): 211-23 PMID29750084show ga
  • Viruses alter host?cell gene expression at many biochemical levels, such as transcription, translation, mRNA splicing and mRNA decay in order to create a cellular environment suitable for viral replication. In this review, we discuss mechanisms by which viruses manipulate host?gene expression at the level of mRNA decay in order to enable the virus to evade host antiviral responses to allow viral survival and replication. We discuss different cellular RNA decay pathways, including the deadenylation-dependent mRNA decay pathway, and various strategies that viruses exploit to manipulate these pathways in order to create a virus-friendly cellular environment.
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