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10.1091/mbc.E17-10-0612 http://scihub22266oqcxt.onion/10.1091/mbc.E17-10-0612 C5935065!5935065!29757705     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Biol+Cell 2018 ; 29 (10): 1153-6 Nephropedia Template TP {{tp|p=29757705|t=2018. Mitotic kinesins in action: diffusive searching, directional switching, and ensemble coordination |pdf=|usr=}}{{29757705}} gab.com Text Mitotic kinesins in action: diffusive searching, directional switching, and ensemble coordination JO: Mol Biol Cell http://www.kidney.de/pget.php?&tw=1&pmid=29757705 #FOAvip Mitotic spindle assembly requires the collective action of multiple microtubule motors that coordinate their activities in ensembles. However, despite significant advances in our understanding of mitotic kinesins at the single-motor level, multi-motor systems are challenging to reconstitute in vitro and thus less well understood. Recent findings highlighted in this perspective demonstrate how various properties of kinesin-5 and -14 motors?diffusive searching, directional switching, and multivalent interactions?allow them to achieve their physiological roles of cross-linking parallel microtubules and sliding antiparallel ones during cell division. Additionally, we highlight new experimental techniques that will help bridge the gap between in vitro biophysical studies and in vivo cell biology investigations and provide new insights into how specific single-molecule mechanisms generate complex cellular behaviors. Twit Text FOAVip Mitotic kinesins in action: diffusive searching, directional switching, and ensemble coordination ????Mol Biol Cell http://www.kidney.de/pget.php?&tw=1&pmid=29757705 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29757705 #FOAvip English Wikipedia <ref>{{Cite pmid|29757705}}</ref> Mitotic kinesins in action: diffusive searching, directional switching, and ensemble coordination #MMPMID29757705 Gicking AM; Qiu W; Hancock WO Mol Biol Cell 2018[May]; 29 (10): 1153-6 PMID29757705show ga Mitotic spindle assembly requires the collective action of multiple microtubule motors that coordinate their activities in ensembles. However, despite significant advances in our understanding of mitotic kinesins at the single-motor level, multi-motor systems are challenging to reconstitute in vitro and thus less well understood. Recent findings highlighted in this perspective demonstrate how various properties of kinesin-5 and -14 motors?diffusive searching, directional switching, and multivalent interactions?allow them to achieve their physiological roles of cross-linking parallel microtubules and sliding antiparallel ones during cell division. Additionally, we highlight new experimental techniques that will help bridge the gap between in vitro biophysical studies and in vivo cell biology investigations and provide new insights into how specific single-molecule mechanisms generate complex cellular behaviors. äMitotic kinesins in action: diffusive searching, directional switching(epmc).pdf DeepDyve Pubget Overpricing