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10.1186/s12882-018-0905-6 http://scihub22266oqcxt.onion/10.1186/s12882-018-0905-6 C5934801!5934801 !29724182     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29724182 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       BMC+Nephrol 2018 ; 19 (1 ): 108 Nephropedia Template TP {{tp|p=29724182 |t=2018. Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report |pdf=|usr=}}{{29724182 }} gab.com Text Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report JO: BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=29724182 #FOAvip BACKGROUND: Complement component 3 (C3) glomerulopathy, which includes dense deposit disease (DDD) and C3 glomerulonephritis, is caused by dysregulation of the alternative complement pathway. In most cases, C3 glomerulopathy manifests pathologically with membranoproliferative glomerulonephritis-like features. An association between C3 glomerulopathy and monoclonal gammopathy was recently reported in several cases, raising the possibility that C3 glomerulopathy is the underlying pathological process in monoclonal gammopathy of renal significance. CASE PRESENTATION: We herein report a case of monoclonal gammopathy-induced DDD that improved histologically and clinically with chemotherapy including bortezomib. Our case is the first in which treatment response can be linked to the histological response. Potential pathological insights are also discussed. CONCLUSIONS: Rapid and efficient chemotherapy has the potential to limit renal damage in monoclonal gammopathy-associated DDD. Twit Text FOAVip Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report ????BMC Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=29724182 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29724182 #FOAvip English Wikipedia <ref>{{Cite pmid|29724182 }}</ref> Favorable effect of bortezomib in dense deposit disease associated with monoclonal gammopathy: a case report #MMPMID29724182 Hirashio S ; Satoh A ; Arima T ; Mandai K ; Awaya T ; Oshima K ; Hara S ; Masaki T BMC Nephrol 2018[May]; 19 (1 ): 108 PMID29724182 show ga BACKGROUND: Complement component 3 (C3) glomerulopathy, which includes dense deposit disease (DDD) and C3 glomerulonephritis, is caused by dysregulation of the alternative complement pathway. In most cases, C3 glomerulopathy manifests pathologically with membranoproliferative glomerulonephritis-like features. An association between C3 glomerulopathy and monoclonal gammopathy was recently reported in several cases, raising the possibility that C3 glomerulopathy is the underlying pathological process in monoclonal gammopathy of renal significance. CASE PRESENTATION: We herein report a case of monoclonal gammopathy-induced DDD that improved histologically and clinically with chemotherapy including bortezomib. Our case is the first in which treatment response can be linked to the histological response. Potential pathological insights are also discussed. CONCLUSIONS: Rapid and efficient chemotherapy has the potential to limit renal damage in monoclonal gammopathy-associated DDD. |Antineoplastic Agents/*therapeutic use [MESH] |Bortezomib/*therapeutic use [MESH] |Complement C3/metabolism [MESH] |Glomerulonephritis, Membranoproliferative/blood/*diagnosis/*drug therapy [MESH] |Humans [MESH] |Male [MESH] |Middle Aged [MESH] |Paraproteinemias/blood/*diagnosis/*drug therapy [MESH]Favorable effect of bortezomib in dense deposit disease associated wit(epmc).pdf DeepDyve Pubget Overpricing