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http://scihub22266oqcxt.onion/ C5934570!5934570!29736204     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transl+Res 2018 ; 10 (4): 1109-16 Nephropedia Template TP {{tp|p=29736204|t=2018. Osthole attenuates myocardial ischemia/reperfusion injury in rats by inhibiting apoptosis and inflammation |pdf=|usr=}}{{29736204}} gab.com Text Osthole attenuates myocardial ischemia/reperfusion injury in rats by inhibiting apoptosis and inflammation JO: Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=29736204 #FOAvip This study was performed to evaluate the cardioprotective effects of osthole (OST) in a rat model of myocardial ischemia/reperfusion injury (MI/RI) and the underlying mechanism. We exposed rat hearts to left anterior descending coronary artery ligation for 30 min followed by 24 h of reperfusion. The results showed that pretreatment with OST ameliorated MI/RI as evidenced by histopathological examination. Moreover, the terminal deoxynucleotidyl transferase dUTP nick end-labeling assay demonstrated that OST suppressed myocardial apoptosis, which may be related to an increase in the Bcl-2/Bax ratio and inhibition of caspase-3 and caspase-9 activation. Furthermore, we determined that OST ameliorated impaired mitochondrial morphology and the oxidation system; OST also attenuated levels of pro-inflammatory cytokines, including tumor necrosis factor ? and interleukins 6 and 1?. In conclusion, OST exerted a strong favorable cardioprotective effect on MI/RI, possibly by suppressing the in?ammatory response and inhibiting cell apoptosis. Twit Text FOAVip Osthole attenuates myocardial ischemia/reperfusion injury in rats by inhibiting apoptosis and inflammation ????Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=29736204 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29736204 #FOAvip English Wikipedia <ref>{{Cite pmid|29736204}}</ref> Osthole attenuates myocardial ischemia/reperfusion injury in rats by inhibiting apoptosis and inflammation #MMPMID29736204 Wu J; Yang Y; Xun N; Zeng L; Li Z; Yang W; Liang Y; Ma Z; Tang H Am J Transl Res 2018[]; 10 (4): 1109-16 PMID29736204show ga This study was performed to evaluate the cardioprotective effects of osthole (OST) in a rat model of myocardial ischemia/reperfusion injury (MI/RI) and the underlying mechanism. We exposed rat hearts to left anterior descending coronary artery ligation for 30 min followed by 24 h of reperfusion. The results showed that pretreatment with OST ameliorated MI/RI as evidenced by histopathological examination. Moreover, the terminal deoxynucleotidyl transferase dUTP nick end-labeling assay demonstrated that OST suppressed myocardial apoptosis, which may be related to an increase in the Bcl-2/Bax ratio and inhibition of caspase-3 and caspase-9 activation. Furthermore, we determined that OST ameliorated impaired mitochondrial morphology and the oxidation system; OST also attenuated levels of pro-inflammatory cytokines, including tumor necrosis factor ? and interleukins 6 and 1?. In conclusion, OST exerted a strong favorable cardioprotective effect on MI/RI, possibly by suppressing the in?ammatory response and inhibiting cell apoptosis. äOsthole attenuates myocardial ischemia/reperfusion injury in rats by i(epmc).pdf DeepDyve Pubget Overpricing