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10.1038/s41598-018-25144-x

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suck abstract from ncbi


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pmid29725035
      Sci+Rep 2018 ; 8 (1 ): 6968
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  • White donor, younger donor and double lung transplant are associated with better survival in sarcoidosis patients #MMPMID29725035
  • Salamo O ; Roghaee S ; Schweitzer MD ; Mantero A ; Shafazand S ; Campos M ; Mirsaeidi M
  • Sci Rep 2018[May]; 8 (1 ): 6968 PMID29725035 show ga
  • Sarcoidosis commonly affects the lung. Lung transplantation (LT) is required when there is a severe and refractory involvement. We compared post-transplant survival rates of sarcoidosis patients with chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). We also explored whether the race and age of the donor, and double lung transplant have any effect on the survival in the post transplant setting. We analyzed 9,727 adult patients with sarcoidosis, COPD, and IPF who underwent LT worldwide between 2005-2015 based on United Network for Organ Sharing (UNOS) database. Survival rates were compared with Kaplan-Meier, and risk factors were investigated by Cox-regression analysis. 469 (5%) were transplanted because of sarcoidosis, 3,688 (38%) for COPD and 5,570 (57%) for IPF. Unadjusted survival analysis showed a better post-transplant survival rate for patients with sarcoidosis (p?
  • |*Donor Selection/methods [MESH]
  • |*Lung Transplantation/methods [MESH]
  • |Adult [MESH]
  • |Age Factors [MESH]
  • |Aged [MESH]
  • |Female [MESH]
  • |Graft Survival [MESH]
  • |Humans [MESH]
  • |Idiopathic Pulmonary Fibrosis/epidemiology/therapy [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Proportional Hazards Models [MESH]
  • |Pulmonary Disease, Chronic Obstructive/epidemiology/therapy [MESH]
  • |Sarcoidosis, Pulmonary/epidemiology/*therapy [MESH]
  • |Survival Analysis [MESH]
  • |Survival Rate [MESH]
  • |Treatment Outcome [MESH]


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