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10.1111/j.1349-7006.2002.tb01313.x http://scihub22266oqcxt.onion/10.1111/j.1349-7006.2002.tb01313.x C5927068!5927068!12149137     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Jpn+J+Cancer+Res 2002 ; 93 (7): 729-35 Nephropedia Template TP {{tp|p=12149137|t=2002. Psychosocial Stress Augments Tumor Development through ??Adrenergic Activation in Mice |pdf=|usr=}}{{12149137}} gab.com Text Psychosocial Stress Augments Tumor Development through Adrenergic Activation in Mice JO: Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=12149137 #FOAvip Housing conditions affect behavioral and biological responses of animals. We investigated the effect of same?sex?grouped (G), crowded (GC) and isolated (I) conditions on the growth of B16 melanoma or Meth A fibrosarcoma implanted in the footpad of syngeneic male C57BL/6 or BALB/c mice. Differential housing altered host resistance to tumor growth. The host responses to stress were reflected in thymic atrophy, which was lowest in the G mice, highest in the GC mice and intermediate in the I mice. The GC condition was a more stressful social environment than the I condition in both male C57BL/6 and BALB/c mice. Reflecting the extent of psychosocial stress, tumor growth was augmented in the order of GC, I and G condition, and a negative mass correlation between tumor and thymus was observed, thus clearly indicating that the host resistance to tumors was attenuated by psychosocial stress. Furthermore, the stress?enhanced tumor growth and thymus atrophy were completely abrogated by the oral administration of the non?selective ??adrenergic antagonist, propranolol. On the contrary, the chronic administration of corticosterone significantly induced the atrophy of thymus and spleen without affecting tumor growth. These results suggest an interrelationship among psychosocial stress, tumor growth and ??adrenergic activation. Twit Text FOAVip Psychosocial Stress Augments Tumor Development through Adrenergic Activation in Mice ????Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=12149137 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=12149137 #FOAvip English Wikipedia <ref>{{Cite pmid|12149137}}</ref> Psychosocial Stress Augments Tumor Development through ??Adrenergic Activation in Mice #MMPMID12149137 Hasegawa H; Saiki I Jpn J Cancer Res 2002[Jul]; 93 (7): 729-35 PMID12149137show ga Housing conditions affect behavioral and biological responses of animals. We investigated the effect of same?sex?grouped (G), crowded (GC) and isolated (I) conditions on the growth of B16 melanoma or Meth A fibrosarcoma implanted in the footpad of syngeneic male C57BL/6 or BALB/c mice. Differential housing altered host resistance to tumor growth. The host responses to stress were reflected in thymic atrophy, which was lowest in the G mice, highest in the GC mice and intermediate in the I mice. The GC condition was a more stressful social environment than the I condition in both male C57BL/6 and BALB/c mice. Reflecting the extent of psychosocial stress, tumor growth was augmented in the order of GC, I and G condition, and a negative mass correlation between tumor and thymus was observed, thus clearly indicating that the host resistance to tumors was attenuated by psychosocial stress. Furthermore, the stress?enhanced tumor growth and thymus atrophy were completely abrogated by the oral administration of the non?selective ??adrenergic antagonist, propranolol. On the contrary, the chronic administration of corticosterone significantly induced the atrophy of thymus and spleen without affecting tumor growth. These results suggest an interrelationship among psychosocial stress, tumor growth and ??adrenergic activation. äPsychosocial Stress Augments Tumor Development through ??Adrenergic Ac(epmc).pdf DeepDyve Pubget Overpricing