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2018 ; 10
(4
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance,
Phage Training and Prophages in Bacterial Production Strains
#MMPMID29621199
Rohde C
; Resch G
; Pirnay JP
; Blasdel BG
; Debarbieux L
; Gelman D
; Górski A
; Hazan R
; Huys I
; Kakabadze E
; ?obocka M
; Maestri A
; Almeida GMF
; Makalatia K
; Malik DJ
; Ma?la?ová I
; Merabishvili M
; Pantucek R
; Rose T
; ?tveráková D
; Van Raemdonck H
; Verbeken G
; Chanishvili N
Viruses
2018[Apr]; 10
(4
): ä PMID29621199
show ga
Phage therapy is increasingly put forward as a "new" potential tool in the fight
against antibiotic resistant infections. During the "Centennial Celebration of
Bacteriophage Research" conference in Tbilisi, Georgia on 26-29 June 2017, an
international group of phage researchers committed to elaborate an expert opinion
on three contentious phage therapy related issues that are hampering clinical
progress in the field of phage therapy. This paper explores and discusses
bacterial phage resistance, phage training and the presence of prophages in
bacterial production strains while reviewing relevant research findings and
experiences. Our purpose is to inform phage therapy stakeholders such as policy
makers, officials of the competent authorities for medicines, phage researchers
and phage producers, and members of the pharmaceutical industry. This brief also
points out potential avenues for future phage therapy research and development as
it specifically addresses those overarching questions that currently call for
attention whenever phages go into purification processes for application.