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10.3390/v10040166 http://scihub22266oqcxt.onion/10.3390/v10040166 C5923460!5923460!29614729     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Viruses 2018 ; 10 (4): ä Nephropedia Template TP {{tp|p=29614729|t=2018. Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton |pdf=|usr=}}{{29614729}} gab.com Text Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=29614729 #FOAvip Viruses have a dual nature: particles are ?passive substances? lacking chemical energy transformation, whereas infected cells are ?active substances? turning-over energy. How passive viral substances convert to active substances, comprising viral replication and assembly compartments has been of intense interest to virologists, cell and molecular biologists and immunologists. Infection starts with virus entry into a susceptible cell and delivers the viral genome to the replication site. This is a multi-step process, and involves the cytoskeleton and associated motor proteins. Likewise, the egress of progeny virus particles from the replication site to the extracellular space is enhanced by the cytoskeleton and associated motor proteins. This overcomes the limitation of thermal diffusion, and transports virions and virion components, often in association with cellular organelles. This review explores how the analysis of viral trajectories informs about mechanisms of infection. We discuss the methodology enabling researchers to visualize single virions in cells by fluorescence imaging and tracking. Virus visualization and tracking are increasingly enhanced by computational analyses of virus trajectories as well as in silico modeling. Combined approaches reveal previously unrecognized features of virus-infected cells. Using select examples of complementary methodology, we highlight the role of actin filaments and microtubules, and their associated motors in virus infections. In-depth studies of single virion dynamics at high temporal and spatial resolutions thereby provide deep insight into virus infection processes, and are a basis for uncovering underlying mechanisms of how cells function. Twit Text FOAVip Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=29614729 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29614729 #FOAvip English Wikipedia <ref>{{Cite pmid|29614729}}</ref> Imaging, Tracking and Computational Analyses of Virus Entry and Egress with the Cytoskeleton #MMPMID29614729 Wang IH; Burckhardt CJ; Yakimovich A; Greber UF Viruses 2018[Apr]; 10 (4): ä PMID29614729show ga Viruses have a dual nature: particles are ?passive substances? lacking chemical energy transformation, whereas infected cells are ?active substances? turning-over energy. How passive viral substances convert to active substances, comprising viral replication and assembly compartments has been of intense interest to virologists, cell and molecular biologists and immunologists. Infection starts with virus entry into a susceptible cell and delivers the viral genome to the replication site. This is a multi-step process, and involves the cytoskeleton and associated motor proteins. Likewise, the egress of progeny virus particles from the replication site to the extracellular space is enhanced by the cytoskeleton and associated motor proteins. This overcomes the limitation of thermal diffusion, and transports virions and virion components, often in association with cellular organelles. This review explores how the analysis of viral trajectories informs about mechanisms of infection. We discuss the methodology enabling researchers to visualize single virions in cells by fluorescence imaging and tracking. Virus visualization and tracking are increasingly enhanced by computational analyses of virus trajectories as well as in silico modeling. Combined approaches reveal previously unrecognized features of virus-infected cells. Using select examples of complementary methodology, we highlight the role of actin filaments and microtubules, and their associated motors in virus infections. In-depth studies of single virion dynamics at high temporal and spatial resolutions thereby provide deep insight into virus infection processes, and are a basis for uncovering underlying mechanisms of how cells function. äImaging, Tracking and Computational Analyses of Virus Entry and Egress(epmc).pdf DeepDyve Pubget Overpricing