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2018 ; 10
(4
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Lumbar Sympathetic Block with Botulinum Toxin Type A and Type B for the Complex
Regional Pain Syndrome
#MMPMID29671801
Lee Y
; Lee CJ
; Choi E
; Lee PB
; Lee HJ
; Nahm FS
Toxins (Basel)
2018[Apr]; 10
(4
): ä PMID29671801
show ga
A lumbar sympathetic ganglion block (LSB) is a therapeutic method for complex
regional pain syndrome (CRPS) affecting the lower limbs. Recently, LSB with
botulinum toxin type A and B was introduced as a novel method to achieve longer
duration of analgesia. In this study, we compared the botulinum toxin type A
(BTA) with botulinum toxin type B (BTB) in performing LSB on patients with CRPS.
LSB was performed with either BTA or BTB on patients with CRPS in their lower
extremities. The length of time taken for patients to return to the pre-LSB pain
score and the adverse effect of LSB with BTA/BTB were investigated. The median
length of time taken for the patients to return to the pre-LSB pain score was 15
days for the BTA group and 69 days for the BTB group (P = 0.002). Scores on a
visual analogue scale decreased in the patients of both groups, and no
significant adverse effects were experienced. In conclusion, the administration
of either BTA or BTB for LSB is a safe method to prolong the sympathetic blocking
effect in patients with CRPS. BTB is more effective than BTA to prolong the
sympathetic blocking effect in CRPS patients.