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10.1007/s00467-013-2638-x http://scihub22266oqcxt.onion/10.1007/s00467-013-2638-x C5922760!5922760!24122260     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Pediatr+Nephrol 2014 ; 29 (2): 315-20 Nephropedia Template TP {{tp|p=24122260|t=2014. A biphasic dialytic strategy for the treatment of neonatal hyperammonemia |pdf=|usr=}}{{24122260}} gab.com Text A biphasic dialytic strategy for the treatment of neonatal hyperammonemia JO: Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=24122260 #FOAvip Background: Neonates with inborn errors of metabolism (IEM) often develop hyperammonemia which, if not corrected quickly, may result in poor neurologic outcomes. As pharmacologic therapy cannot rapidly lower ammonia levels, dialysis is frequently required. Both hemodialysis (HD) and standard-dose continuous renal replacement therapy (CRRT) are effective; however, HD may be followed by post-dialytic ammonia rebound, and standard-dose CRRT may not effect a rapid enough decrease in ammonia levels. Case-Diagnosis/Treatment: We present two cases of IEM-associated neonatal hyperammonemia in which we employed a biphasic, high-dose CRRT treatment strategy, initially using dialysate flow rates of 5,000 mL/h (approximately 40,000 mL/h/1.73 m2) in order to rapidly decrease ammonia levels, then decreasing the dialysate flow rates to 500 mL/h (approximately 4,000 mL/h/1.73 m2) in order to prevent ammonia rebound. Conclusions: This biphasic dialytic treatment strategy for neonatal hyperammonemia effected rapid ammonia reduction without rebound and accomplished during a single dialysis run without equipment changes. Twit Text FOAVip A biphasic dialytic strategy for the treatment of neonatal hyperammonemia ????Pediatr Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=24122260 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24122260 #FOAvip English Wikipedia <ref>{{Cite pmid|24122260}}</ref> A biphasic dialytic strategy for the treatment of neonatal hyperammonemia #MMPMID24122260 Hanudel M; Avasare S; Tsai E; Yadin O; Zaritsky J Pediatr Nephrol 2014[Feb]; 29 (2): 315-20 PMID24122260show ga Background: Neonates with inborn errors of metabolism (IEM) often develop hyperammonemia which, if not corrected quickly, may result in poor neurologic outcomes. As pharmacologic therapy cannot rapidly lower ammonia levels, dialysis is frequently required. Both hemodialysis (HD) and standard-dose continuous renal replacement therapy (CRRT) are effective; however, HD may be followed by post-dialytic ammonia rebound, and standard-dose CRRT may not effect a rapid enough decrease in ammonia levels. Case-Diagnosis/Treatment: We present two cases of IEM-associated neonatal hyperammonemia in which we employed a biphasic, high-dose CRRT treatment strategy, initially using dialysate flow rates of 5,000 mL/h (approximately 40,000 mL/h/1.73 m2) in order to rapidly decrease ammonia levels, then decreasing the dialysate flow rates to 500 mL/h (approximately 4,000 mL/h/1.73 m2) in order to prevent ammonia rebound. Conclusions: This biphasic dialytic treatment strategy for neonatal hyperammonemia effected rapid ammonia reduction without rebound and accomplished during a single dialysis run without equipment changes. äA biphasic dialytic strategy for the treatment of neonatal hyperammone(epmc).pdf DeepDyve Pubget Overpricing