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10.1111/j.1349-7006.1996.tb00284.x http://scihub22266oqcxt.onion/10.1111/j.1349-7006.1996.tb00284.x C5921150!5921150!8698622     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Jpn+J+Cancer+Res 1996 ; 87 (7): 724-9 Nephropedia Template TP {{tp|p=8698622|t=1996. Rejection of Mouse Renal Cell Carcinoma Elicited by Local Secretion of Interleukin?2 |pdf=|usr=}}{{8698622}} gab.com Text Rejection of Mouse Renal Cell Carcinoma Elicited by Local Secretion of Interleukin 2 JO: Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=8698622 #FOAvip We introduced the interleukin?2 (IL?2) gene into mouse renal cell carcinoma (RenCa) in order to examine the mechanism of tumor rejection. IL?2 gene?transfected RenCa (RenCa/IL?2Hi) exhibited marked retardation of tumor growth when implanted in a syngeneic host. Growth retardation of RenCa/IL?2Hi was also observed in athymic nude mice even after depletion of natural killer (NK) cells by treatment with anti?asialo GM1 antibody. Histological analysis of RenCa/IL?2Hi tumors disclosed non?specific inflammatory changes in syngeneic hosts. Co?injection of Bacillus Calmette Guerin with RenCa/IL?2Hi considerably enhanced the anti?tumor effects. Taken together, these findings strongly suggest that in situ IL?2 production leads to tumor rejection through non?specific inflammatory responses without participation of T cells and NK cells. On the other hand, the syngeneic mice that had rejected RenCa/IL?2Hi acquired immunity against parental RenCa, suggesting possible participation of memory T cells in the second rejection of the tumor. Twit Text FOAVip Rejection of Mouse Renal Cell Carcinoma Elicited by Local Secretion of Interleukin 2 ????Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=8698622 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=8698622 #FOAvip English Wikipedia <ref>{{Cite pmid|8698622}}</ref> Rejection of Mouse Renal Cell Carcinoma Elicited by Local Secretion of Interleukin?2 #MMPMID8698622 Hara I; Hotta H; Sato N; Eto H; Arakawa S; Kamidono S Jpn J Cancer Res 1996[Jul]; 87 (7): 724-9 PMID8698622show ga We introduced the interleukin?2 (IL?2) gene into mouse renal cell carcinoma (RenCa) in order to examine the mechanism of tumor rejection. IL?2 gene?transfected RenCa (RenCa/IL?2Hi) exhibited marked retardation of tumor growth when implanted in a syngeneic host. Growth retardation of RenCa/IL?2Hi was also observed in athymic nude mice even after depletion of natural killer (NK) cells by treatment with anti?asialo GM1 antibody. Histological analysis of RenCa/IL?2Hi tumors disclosed non?specific inflammatory changes in syngeneic hosts. Co?injection of Bacillus Calmette Guerin with RenCa/IL?2Hi considerably enhanced the anti?tumor effects. Taken together, these findings strongly suggest that in situ IL?2 production leads to tumor rejection through non?specific inflammatory responses without participation of T cells and NK cells. On the other hand, the syngeneic mice that had rejected RenCa/IL?2Hi acquired immunity against parental RenCa, suggesting possible participation of memory T cells in the second rejection of the tumor. äRejection of Mouse Renal Cell Carcinoma Elicited by Local Secretion of(epmc).pdf DeepDyve Pubget Overpricing