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10.1111/j.1349-7006.1996.tb00220.x http://scihub22266oqcxt.onion/10.1111/j.1349-7006.1996.tb00220.x C5921093!5921093!8613433     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Jpn+J+Cancer+Res 1996 ; 87 (3): 296-304 Nephropedia Template TP {{tp|p=8613433|t=1996. Distribution of Transforming Growth Factor?? and Its Receptors in Gastric Carcinoma Tissue |pdf=|usr=}}{{8613433}} gab.com Text Distribution of Transforming Growth Factor and Its Receptors in Gastric Carcinoma Tissue JO: Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=8613433 #FOAvip The distribution of the three mammalian isoforms of transforming growth factor (TGF)?? (TGF??1,??2, and ??3) as well as their signaling receptors, TGF?? type I and type II receptors (T?R?I and T?R?II, respectively), in gastric carcinoma tissue was examined by immunohistochemistry using specific antibodies. Tissue specimens were obtained from 25 cases of gastric carcinoma, which were classified into two groups according to Lauren's classification, i.e. 15 cases of diffuse carcinoma and 10 cases of intestinal carcinoma. In normal gastric mucosa apart from carcinoma nests, all of TGF??1, ??2, ??3, T?R?I and T?R?II were clearly demonstrated in fundic glands. In sharp contrast, none of them was detectable in surface mucous cells. In carcinoma cells, strong staining for TGF??1, ??2 and ?3 was obtained only in diffuse?type carcinoma. In particular, carcinoma cells scattered as single cells or small nests had a tendency to show strong staining for TGF??s. The receptors tended to be distributed concomitantly with the ligands, and diffuse?type carcinoma showed stronger receptor staining than intestinal?type carcinoma. In cancer stroma, TGF??s and receptors were detected in both diffuse and intestinal types, but the area with positive staining was wider and more dispersed in diffuse?type carcinoma than in intestinal carcinoma. These results suggest that TGF?? may contribute in part to the variety of histogenesis and mode of progression of gastric carcinoma. Twit Text FOAVip Distribution of Transforming Growth Factor and Its Receptors in Gastric Carcinoma Tissue ????Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=8613433 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=8613433 #FOAvip English Wikipedia <ref>{{Cite pmid|8613433}}</ref> Distribution of Transforming Growth Factor?? and Its Receptors in Gastric Carcinoma Tissue #MMPMID8613433 Kai T; Taketazu F; Kawakami M; Shimanuki K; Yamada S; Miyazono K; Kato M; Miyata M Jpn J Cancer Res 1996[Mar]; 87 (3): 296-304 PMID8613433show ga The distribution of the three mammalian isoforms of transforming growth factor (TGF)?? (TGF??1,??2, and ??3) as well as their signaling receptors, TGF?? type I and type II receptors (T?R?I and T?R?II, respectively), in gastric carcinoma tissue was examined by immunohistochemistry using specific antibodies. Tissue specimens were obtained from 25 cases of gastric carcinoma, which were classified into two groups according to Lauren's classification, i.e. 15 cases of diffuse carcinoma and 10 cases of intestinal carcinoma. In normal gastric mucosa apart from carcinoma nests, all of TGF??1, ??2, ??3, T?R?I and T?R?II were clearly demonstrated in fundic glands. In sharp contrast, none of them was detectable in surface mucous cells. In carcinoma cells, strong staining for TGF??1, ??2 and ?3 was obtained only in diffuse?type carcinoma. In particular, carcinoma cells scattered as single cells or small nests had a tendency to show strong staining for TGF??s. The receptors tended to be distributed concomitantly with the ligands, and diffuse?type carcinoma showed stronger receptor staining than intestinal?type carcinoma. In cancer stroma, TGF??s and receptors were detected in both diffuse and intestinal types, but the area with positive staining was wider and more dispersed in diffuse?type carcinoma than in intestinal carcinoma. These results suggest that TGF?? may contribute in part to the variety of histogenesis and mode of progression of gastric carcinoma. äDistribution of Transforming Growth Factor?? and Its Receptors in Gast(epmc).pdf DeepDyve Pubget Overpricing