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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Jpn+J+Cancer+Res
1996 ; 87
(3
): 221-6
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The U S -Japan Cooperative Cancer Research Program: some highlights of seminars,
interdisciplinary program area, 1981-1996
#MMPMID8613422
Miller RW
Jpn J Cancer Res
1996[Mar]; 87
(3
): 221-6
PMID8613422
show ga
Thirty-one seminars have been held in the 16 years since 1981. A principal
interest from the beginning was the genetics of cancer, well before this subject
became widely popular. This interest arose in part because of marked binational
differences in type-specific cancer rates, such as the very low rates among
Japanese for Hodgkin's disease in the young, testicular cancer, Ewing's sarcoma,
superficial spreading melanoma, chronic lymphocytic leukemia, and Wilms' tumor
(half the U.S. frequency). Three seminars were devoted to the seeming reciprocal
relationship between B-cell lymphoma (low in Japan) and certain autoimmune
diseases (high in Japan), which is perhaps similar in origin to the male/female
differences in the rates for these diseases. A seminar on Li-Fraumeni syndrome
led to the recognition of cases among Japanese pedigrees brought to the meeting,
and generated a study of its occurrence in Japanese families with adrenocortical
carcinoma in a child. Another seminar revealed a marked clustering of rare
cancers in Werner's (premature aging) syndrome in Japan, and led to a binational
study and analysis of case-reports worldwide. Three seminars on pathology
heightened appreciation of the importance of subclassifying cancer by subsite and
subtype for racial and other comparisons. Four seminars on biostatistics in
cancer research generated a substantial exchange of specialists and trainees in
this field.