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10.1111/j.1349-7006.1995.tb03051.x http://scihub22266oqcxt.onion/10.1111/j.1349-7006.1995.tb03051.x C5920818!5920818 !7744698     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=7744698 &cmd=llinks): Failed to open stream: HTTP request failed! 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Over-expressed ZF5 gene product, a c-myc-binding protein related to GL1-Kruppel protein, has a growth-suppressive activity in mouse cell lines |pdf=|usr=}}{{7744698 }} gab.com Text Over-expressed ZF5 gene product, a c-myc-binding protein related to GL1-Kruppel protein, has a growth-suppressive activity in mouse cell lines JO: Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=7744698 #FOAvip ZF5 encodes a zinc finger protein, which contains five C2H2-type zinc fingers showing homology with the zinc finger of the Kruppel family, and binds to two sites in the mouse c-myc promoter. We report the effect of over-expression of ZF5 on cell growth. ZnCl2 treatment suppressed the growth of a mouse fibroblast cell line (L cells) transfected with the wild-type ZF5 gene driven by the metallothionein promoter. Cells transfected with the wild-type ZF5 gene formed colonies two- to fivefold less efficiently than those transfected with the mutant ZF5 gene in P19, NIH3T3, 3T3-L1 and L cells. Over-expression of ZF5 did not cause c-myc down-regulation or arrest of the cell cycle, but increased the DNA content. Twit Text FOAVip Over-expressed ZF5 gene product, a c-myc-binding protein related to GL1-Kruppel protein, has a growth-suppressive activity in mouse cell lines ????Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=7744698 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=7744698 #FOAvip English Wikipedia <ref>{{Cite pmid|7744698 }}</ref> Over-expressed ZF5 gene product, a c-myc-binding protein related to GL1-Kruppel protein, has a growth-suppressive activity in mouse cell lines #MMPMID7744698 Numoto M ; Yokoro K ; Yanagihara K ; Kamiya K ; Niwa O Jpn J Cancer Res 1995[Mar]; 86 (3 ): 277-83 PMID7744698 show ga ZF5 encodes a zinc finger protein, which contains five C2H2-type zinc fingers showing homology with the zinc finger of the Kruppel family, and binds to two sites in the mouse c-myc promoter. We report the effect of over-expression of ZF5 on cell growth. ZnCl2 treatment suppressed the growth of a mouse fibroblast cell line (L cells) transfected with the wild-type ZF5 gene driven by the metallothionein promoter. Cells transfected with the wild-type ZF5 gene formed colonies two- to fivefold less efficiently than those transfected with the mutant ZF5 gene in P19, NIH3T3, 3T3-L1 and L cells. Over-expression of ZF5 did not cause c-myc down-regulation or arrest of the cell cycle, but increased the DNA content. |*DNA-Binding Proteins [MESH] |*Gene Expression [MESH] |*Transcription Factors [MESH] |*Zinc Fingers [MESH] |3T3 Cells [MESH] |Animals [MESH] |Binding Sites [MESH] |Cell Division/*drug effects [MESH] |Cell Line [MESH] |Chlorides/pharmacology [MESH] |DNA/*metabolism [MESH] |Kruppel-Like Transcription Factors [MESH] |L Cells [MESH] |Mice [MESH] |Promoter Regions, Genetic [MESH] |Repressor Proteins/*genetics/pharmacology [MESH] |Transfection [MESH]Over-expressed ZF5 gene product, a c-myc-binding protein related to GL(epmc).pdf DeepDyve Pubget Overpricing