Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29731827
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29731827
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Exp+Ther+Med
2018 ; 15
(5
): 4426-4430
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Leptin, hs-CRP, IL-18 and urinary protein before and after treatment of children
with nephrotic syndrome
#MMPMID29731827
Zhou J
; Shi F
; Xun W
Exp Ther Med
2018[May]; 15
(5
): 4426-4430
PMID29731827
show ga
We aimed to analyze the changes in plasma leptin, serum inflammatory factors and
urinary protein in children with nephrotic syndrome before and after treatment
and their clinical significance. A total of 28 children treated and diagnosed
with nephrotic syndrome between November 2015 and October 2016 were selected as
treatment group, while 25 healthy children were selected as control group. There
were no statistically significant differences in age, sex, body mass index (BMI),
serum albumin and other general data between treatment group and control group
(P>0.05). There was a positive correlation between serum high-sensitivity
C-reactive protein (hs-CRP) level and 24 h urinary protein level in children with
nephrotic syndrome before treatment (r=0.408, P=0.005). Twenty-four hours urinary
protein, urea nitrogen (BUN) and serum creatinine (SCr) levels in children with
nephrotic syndrome before treatment were significantly higher than those in
normal children, and these indexes were significantly decreased after treatment.
The levels of plasma leptin and serum inflammatory factors (hs-CRP and IL-18) in
children with nephrotic syndrome before treatment were obviously higher than
those in normal children, and these indexes were obviously decreased after
treatment. In conclusion, the detection of changes in plasma leptin, serum
inflammatory factors (hs-CRP and IL-18) and urinary protein in children with
nephrotic syndrome before and after treatment has important reference value for
reflecting the severity of disease and evaluating the prognosis of children with
nephrotic syndrome.