Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3389/fimmu.2018.00763 http://scihub22266oqcxt.onion/10.3389/fimmu.2018.00763 C5920033!5920033!29731751     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2018 ; 9 (ä): ä Nephropedia Template TP {{tp|p=29731751|t=2018. Unique Action of Interleukin-18 on T Cells and Other Immune Cells |pdf=|usr=}}{{29731751}} gab.com Text Unique Action of Interleukin-18 on T Cells and Other Immune Cells JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29731751 #FOAvip Interleukin (IL)-18 was originally discovered as a factor that enhances interferon (IFN)-? production by anti-CD3-stimulated Th1?cells, particularly in association with IL-12. IL-12 is a cytokine that induces development of Th1?cells. IL-18 cannot induce Th1?cell development, but has the capacity to activate established Th1?cells to produce IFN-? in the presence of IL-12. Thus, IL-18 is regarded as a proinflammatory cytokine that facilitates type 1 responses. However, in the absence of IL-12 but presence of IL-2, IL-18 stimulates natural killer cells, NKT cells, and even established Th1?cells to produce IL-3, IL-9, and IL-13. Thus, IL-18 also facilitates type 2 responses. This unique function of IL-18 contributes to infection-associated allergic diseases. Together with IL-3, IL-18 stimulates mast cells and basophils to produce IL-4, IL-13, and chemical mediators such as histamine. Thus, IL-18 also induces innate-type allergic inflammation. IL-18 belongs to the IL-1 family of cytokines, which share similar molecular structures, receptors structures, and signal transduction pathways. Nevertheless, IL-18 shows a unique function by binding to a specific receptor expressed on distinct types of cells. In this review article, I will focus on the unique features of IL-18 in lymphocytes, basophils, and mast cells, particularly in comparison with IL-33. Twit Text FOAVip Unique Action of Interleukin-18 on T Cells and Other Immune Cells ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=29731751 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29731751 #FOAvip English Wikipedia <ref>{{Cite pmid|29731751}}</ref> Unique Action of Interleukin-18 on T Cells and Other Immune Cells #MMPMID29731751 Nakanishi K Front Immunol 2018[]; 9 (ä): ä PMID29731751show ga Interleukin (IL)-18 was originally discovered as a factor that enhances interferon (IFN)-? production by anti-CD3-stimulated Th1?cells, particularly in association with IL-12. IL-12 is a cytokine that induces development of Th1?cells. IL-18 cannot induce Th1?cell development, but has the capacity to activate established Th1?cells to produce IFN-? in the presence of IL-12. Thus, IL-18 is regarded as a proinflammatory cytokine that facilitates type 1 responses. However, in the absence of IL-12 but presence of IL-2, IL-18 stimulates natural killer cells, NKT cells, and even established Th1?cells to produce IL-3, IL-9, and IL-13. Thus, IL-18 also facilitates type 2 responses. This unique function of IL-18 contributes to infection-associated allergic diseases. Together with IL-3, IL-18 stimulates mast cells and basophils to produce IL-4, IL-13, and chemical mediators such as histamine. Thus, IL-18 also induces innate-type allergic inflammation. IL-18 belongs to the IL-1 family of cytokines, which share similar molecular structures, receptors structures, and signal transduction pathways. Nevertheless, IL-18 shows a unique function by binding to a specific receptor expressed on distinct types of cells. In this review article, I will focus on the unique features of IL-18 in lymphocytes, basophils, and mast cells, particularly in comparison with IL-33. äUnique Action of Interleukin-18 on T Cells and Other Immune Cells (epmc).pdf DeepDyve Pubget Overpricing