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10.1111/j.1349-7006.1991.tb01903.x http://scihub22266oqcxt.onion/10.1111/j.1349-7006.1991.tb01903.x C5918512!5918512!1649811     free     free     free       Jpn+J+Cancer+Res 1991 ; 82 (6): 676-85 Nephropedia Template TP {{tp|p=1649811|t=1991. Epigenetic Control of Tumor Cell Morphology |pdf=|usr=}}{{1649811}} gab.com Text Epigenetic Control of Tumor Cell Morphology JO: Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=1649811 #FOAvip XC cell line derived from a single rat cell transformed by the Prague strain of Rons sarcoma virus produced morphologically different colonies. Among them, two distinct cell types consisting of thick, fusiform cells (L?type), and of flat, polygonal cells (R?type) were apparent. By repeated subclonings, pure cultures, L1 and R1, respectively, were obtained. These clones underwent morphological conversion during prolonged culture; L?type colonies appeared in the R?type clone and vice versa. The kinetic curve suggested that the conversion was multi?stepped. When inoculated into nude mice, L?type cells produced much larger tumors at a higher frequency than R?type cells, and the tumors induced by these two clones were histologically different. The expression of v?src gene was higher in L?type than in R?type cells at both mRNA and protein levels. Twit Text FOAVip Epigenetic Control of Tumor Cell Morphology ????Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=1649811 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=1649811 #FOAvip English Wikipedia <ref>{{Cite pmid|1649811}}</ref> Epigenetic Control of Tumor Cell Morphology #MMPMID1649811 Horio K; Yoshikura H; Kawabata M; Odawara T; Sudo K; Fujitani Y; Lee G; Iwamoto A Jpn J Cancer Res 1991[Jun]; 82 (6): 676-85 PMID1649811show ga XC cell line derived from a single rat cell transformed by the Prague strain of Rons sarcoma virus produced morphologically different colonies. Among them, two distinct cell types consisting of thick, fusiform cells (L?type), and of flat, polygonal cells (R?type) were apparent. By repeated subclonings, pure cultures, L1 and R1, respectively, were obtained. These clones underwent morphological conversion during prolonged culture; L?type colonies appeared in the R?type clone and vice versa. The kinetic curve suggested that the conversion was multi?stepped. When inoculated into nude mice, L?type cells produced much larger tumors at a higher frequency than R?type cells, and the tumors induced by these two clones were histologically different. The expression of v?src gene was higher in L?type than in R?type cells at both mRNA and protein levels. äEpigenetic Control of Tumor Cell Morphology (epmc).pdf DeepDyve Pubget Overpricing