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10.1111/j.1349-7006.1988.tb01601.x http://scihub22266oqcxt.onion/10.1111/j.1349-7006.1988.tb01601.x C5917474!5917474 !3131285     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\3131285 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Jpn+J+Cancer+Res 1988 ; 79 (3 ): 375-83 Nephropedia Template TP {{tp|p=3131285 |t=1988. The mechanisms of cytotoxicity to tumor cells by polymorphonuclear leukocytes stimulated with cytokines |pdf=|usr=}}{{3131285 }} gab.com Text The mechanisms of cytotoxicity to tumor cells by polymorphonuclear leukocytes stimulated with cytokines JO: Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=3131285 #FOAvip The mechanisms of tumor cytotoxicity of rat polymorphonuclear leukocytes (PMN) activated with cytokine(s) were studied with the use of supernatants from a rat myelomonocytic leukemia cell line, WRT-7, incubated in the presence of bacterial lipopolysaccharide (LPS) (LPS WRT-7 sup) as a source of cytokine. Rat peritoneal PMN treated with LPS WRT-7 sup showed cytostasis from 3 hr after the start of incubation, while significant cytolysis was first observed after 24 hr. When target tumor cells were separated from PMN at 6 or 12 hr after the start of the assay, 3H-UdR release from the separated target cells comparable to that from the group incubated with PMN for the whole assay time of 40 hr was observed during the following incubation, which indicates that priming for subsequent lysis occurs at a relatively early stage of the assay. None of various scavengers of active oxygens, inhibitors of heme enzymes, and inhibitors of neutral proteinases inhibited cytolysis mediated by PMN stimulated with LPS WRT-7 sup. Heparin inhibited PMN cytolysis only when it was added within 1 hr after the start of the assay. Fractionation of heparin by ion exchange chromatography showed a parallelism between the negative charge and the inhibitory effect of heparin on PMN cytotoxicity. Twit Text FOAVip The mechanisms of cytotoxicity to tumor cells by polymorphonuclear leukocytes stimulated with cytokines ????Jpn J Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=3131285 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=3131285 #FOAvip English Wikipedia <ref>{{Cite pmid|3131285 }}</ref> The mechanisms of cytotoxicity to tumor cells by polymorphonuclear leukocytes stimulated with cytokines #MMPMID3131285 Hayashi T ; Arai S ; Sendo F Jpn J Cancer Res 1988[Mar]; 79 (3 ): 375-83 PMID3131285 show ga The mechanisms of tumor cytotoxicity of rat polymorphonuclear leukocytes (PMN) activated with cytokine(s) were studied with the use of supernatants from a rat myelomonocytic leukemia cell line, WRT-7, incubated in the presence of bacterial lipopolysaccharide (LPS) (LPS WRT-7 sup) as a source of cytokine. Rat peritoneal PMN treated with LPS WRT-7 sup showed cytostasis from 3 hr after the start of incubation, while significant cytolysis was first observed after 24 hr. When target tumor cells were separated from PMN at 6 or 12 hr after the start of the assay, 3H-UdR release from the separated target cells comparable to that from the group incubated with PMN for the whole assay time of 40 hr was observed during the following incubation, which indicates that priming for subsequent lysis occurs at a relatively early stage of the assay. None of various scavengers of active oxygens, inhibitors of heme enzymes, and inhibitors of neutral proteinases inhibited cytolysis mediated by PMN stimulated with LPS WRT-7 sup. Heparin inhibited PMN cytolysis only when it was added within 1 hr after the start of the assay. Fractionation of heparin by ion exchange chromatography showed a parallelism between the negative charge and the inhibitory effect of heparin on PMN cytotoxicity. |*Cell Survival/drug effects [MESH] |Animals [MESH] |Biological Products/*pharmacology [MESH] |Cell Line [MESH] |Cell-Free System [MESH] |Cytokines [MESH] |Free Radicals [MESH] |Heparin/pharmacology [MESH] |Humans [MESH] |Kinetics [MESH] |Leukemia, Myeloid/pathology [MESH] |Lipopolysaccharides/pharmacology [MESH] |Male [MESH] |Mice [MESH] |Neutrophils/drug effects/metabolism/*physiology [MESH] |Oxygen/toxicity [MESH] |Rats [MESH]The mechanisms of cytotoxicity to tumor cells by polymorphonuclear leu(epmc).pdf DeepDyve Pubget Overpricing