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10.1016/j.matbio.2014.03.001 http://scihub22266oqcxt.onion/10.1016/j.matbio.2014.03.001 C5916777!5916777!24657887     free     free     free       Matrix+Biol 2014 ; 37 (ä): 131-41 Nephropedia Template TP {{tp|p=24657887|t=2014. Role of osteopontin in the pathophysiology of cancer |pdf=|usr=}}{{24657887}} gab.com Text Role of osteopontin in the pathophysiology of cancer JO: Matrix Biol http://www.kidney.de/pget.php?&tw=1&pmid=24657887 #FOAvip Osteopontin (OPN) is a multifunctional cytokine that impacts cell proliferation, survival, drug resistance, invasion, and stem like behavior. Due to its critical involvement in regulating cellular functions, its aberrant expression and/or splicing is functionally responsible for undesirable alterations in disease pathologies, specifically cancer. It is implicated in promoting invasive and metastatic progression of many carcinomas. Due to its autocrine and paracrine activities OPN has been shown to be a crucial mediator of cellular cross talk and an influential factor in the tumor microenvironment. OPN has been implicated as a prognostic and diagnostic marker for several cancer types. It has also been explored as a possible target for treatment. In this article we hope to provide a broad perspective on the importance of OPN in the pathophysiology of cancer. Twit Text FOAVip Role of osteopontin in the pathophysiology of cancer ????Matrix Biol http://www.kidney.de/pget.php?&tw=1&pmid=24657887 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24657887 #FOAvip English Wikipedia <ref>{{Cite pmid|24657887}}</ref> Role of osteopontin in the pathophysiology of cancer #MMPMID24657887 Shevde LA; Samant RS Matrix Biol 2014[Jul]; 37 (ä): 131-41 PMID24657887show ga Osteopontin (OPN) is a multifunctional cytokine that impacts cell proliferation, survival, drug resistance, invasion, and stem like behavior. Due to its critical involvement in regulating cellular functions, its aberrant expression and/or splicing is functionally responsible for undesirable alterations in disease pathologies, specifically cancer. It is implicated in promoting invasive and metastatic progression of many carcinomas. Due to its autocrine and paracrine activities OPN has been shown to be a crucial mediator of cellular cross talk and an influential factor in the tumor microenvironment. OPN has been implicated as a prognostic and diagnostic marker for several cancer types. It has also been explored as a possible target for treatment. In this article we hope to provide a broad perspective on the importance of OPN in the pathophysiology of cancer. äRole of osteopontin in the pathophysiology of cancer (epmc).pdf DeepDyve Pubget Overpricing