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10.3389/fendo.2018.00169

http://scihub22266oqcxt.onion/10.3389/fendo.2018.00169
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C5913278!5913278!29719529
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suck abstract from ncbi


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pmid29719529      Front+Endocrinol+(Lausanne) 2018 ; 9 (ä): ä
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  • ANGPTL8: An Important Regulator in Metabolic Disorders #MMPMID29719529
  • Luo M; Peng D
  • Front Endocrinol (Lausanne) 2018[]; 9 (ä): ä PMID29719529show ga
  • Long-term controversy regarding the role of angiopoietin-like protein 8 (ANGPTL8) in beta-cell proliferation and diabetes progression made it a research spotlight. Recently, the controversy was resolved. Although ANGPTL8 could not control beta-cell expansion and islet function, ANGPTL8 was still considered as a novel but atypical member in the ANGPTL family because of its unique structure and crucial effects on lipid metabolism. Besides, ANGPTL8 also participated in some other disorders such as non-alcoholic fatty liver disease and renal dysfunction. Understanding the features of ANGPTL8 may offer new diagnostic and therapeutic approaches to metabolic-related diseases. Therefore, we reviewed most recent findings about ANGPTL8 and aimed to provide an integrated picture of ANGPTL8.
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