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2018 ; 97
(15
): e0285
Nephropedia Template TP
gab.com Text
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Full recovery after prolonged resuscitation from cardiac arrest due to
propafenone intoxication: A case report
#MMPMID29642149
Ling B
; Geng P
; Tan D
; Walline J
Medicine (Baltimore)
2018[Apr]; 97
(15
): e0285
PMID29642149
show ga
RATIONALE: The prognosis of cardiac arrest (CA) induced by propafenone
intoxication was thought to be very poor. The maximal duration of cardiopulmonary
resuscitation (CPR) for propafenone induced CA is unknown. PATIENT CONCERNS: We
describe a case that was successfully resuscitated after prolonged CPR (totaling
340 minutes during one hospital visit) for propafenone intoxication without
subsequent neurological sequela. DIAGNOSES: A previously healthy 36-year-old
female who developed multiple and prolonged CAs after consuming 98 tablets of
50mg propafenone. The CPR duration of this case, to the best of our knowledge, is
the longest of all existing propafenone-induced CPR events to still have full
recovery. We also analyse the contributing factors to this successful CPR.
INTERVENTIONS: Sodium bicarbonate, inotropic drugs and pacemaker application did
not prevent the occurrence of CA. A full recovery was eventually achieved after
prolonged CPR with a mechanical CPR device, blood purification and other
aggressive supportive treatments. OUTCOMES: Full recovery without neurological
sequela. LESSONS: Prolonged CPR including the application of mechanical CPR
devices should be considered in propafenone-related CA, especially in young
patients without significant comorbidities and delayed resuscitation.