Cumulus cells affect distribution and function of the cytoskeleton and organelles
in porcine oocytes
#MMPMID29699248
Suzuki H
; Saito Y
Reprod Med Biol
2006[Sep]; 5
(3
): 183-194
PMID29699248
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Mammalian oocytes grow and undergo meiosis within ovarian follicles. Oocytes are
arrested at the first meiotic prophase, being controlled or influenced by
follicular somatic cells. Under the influence of gonadotropins, immature oocytes
resume meiosis. During meiotic progression, some cytoplasmic changes occur,
so-called cytoplasmic maturation. However, porcine follicular oocytes vary
greatly in developmental competence. The present review summarizes recent studies
highlighting the importance of cumulus cells in maintaining the developmental
ability and in reorganizing the cytoskeleton and organelles of porcine oocytes.
Factors affecting wide variation of the nuclear and cytoplasmic maturation
observed in the porcine oocytes are discussed. (Reprod Med Biol 2006; 5:
183-194).