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10.1046/j.1445-5781.2003.00016.x http://scihub22266oqcxt.onion/10.1046/j.1445-5781.2003.00016.x C5904681!5904681!29699162     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Reprod+Med+Biol 2003 ; 2 (1): 1-24 Nephropedia Template TP {{tp|p=29699162|t=2003. Insulin?like growth factors and their binding proteins: Potential relevance to reproductive physiology |pdf=|usr=}}{{29699162}} gab.com Text Insulin like growth factors and their binding proteins: Potential relevance to reproductive physiology JO: Reprod Med Biol http://www.kidney.de/pget.php?&tw=1&pmid=29699162 #FOAvip Cyclic ovarian follicular development is a complex process that involves proliferation, differentiation, and death of follicle cells. Gonadotropins produced by the pituitary gland have a central role in the regulation of these processes. In addition, a wide range of paracrine and autocrine factors produced in the reproductive organs have been proposed as regulators of reproductive functions. Components of the insulin?like growth factors (IGF) system are widely expressed in the female reproductive tract. The IGFs and their binding proteins play a significant role in several processes of reproductive physiology, including ovarian follicular development, oogenesis and oocyte maturation, ovulation, luteal function, follicular atresia, and testicular function. The majority of these physiological actions of the IGFs are believed to occur via activation of the IGF?I receptor, although the IGF?I effects are modulated by IGF binding proteins (IGFBPs). As much of the data obtained to date have been in the rodent reproductive organs, it may not be possible to directly extrapolate the results to the primate organs. There is a distinct species?difference in the gene expression and functional roles of the IGF?IGFBP system in reproductive organs. However, the disturbance of the IGF?IGFBP system in human reproductive physiology may lead to anovulation, disorders of androgen excess, infertility associated with implantation failure, and male infertility. Further research is needed in domestic animals to determine if manipulation of the IGF?IGFBP system may result in improved reproductive efficiency. As our understanding of the IGF?IGFBP system increases, the uses of human recombinant IGF peptides and IGFBPs as clinical therapy for disease states is becoming a reality. (Reprod Med Biol 2003; 2: 1?24) Twit Text FOAVip Insulin like growth factors and their binding proteins: Potential relevance to reproductive physiology ????Reprod Med Biol http://www.kidney.de/pget.php?&tw=1&pmid=29699162 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29699162 #FOAvip English Wikipedia <ref>{{Cite pmid|29699162}}</ref> Insulin?like growth factors and their binding proteins: Potential relevance to reproductive physiology #MMPMID29699162 Yoshimura Y Reprod Med Biol 2003[Mar]; 2 (1): 1-24 PMID29699162show ga Cyclic ovarian follicular development is a complex process that involves proliferation, differentiation, and death of follicle cells. Gonadotropins produced by the pituitary gland have a central role in the regulation of these processes. In addition, a wide range of paracrine and autocrine factors produced in the reproductive organs have been proposed as regulators of reproductive functions. Components of the insulin?like growth factors (IGF) system are widely expressed in the female reproductive tract. The IGFs and their binding proteins play a significant role in several processes of reproductive physiology, including ovarian follicular development, oogenesis and oocyte maturation, ovulation, luteal function, follicular atresia, and testicular function. The majority of these physiological actions of the IGFs are believed to occur via activation of the IGF?I receptor, although the IGF?I effects are modulated by IGF binding proteins (IGFBPs). As much of the data obtained to date have been in the rodent reproductive organs, it may not be possible to directly extrapolate the results to the primate organs. There is a distinct species?difference in the gene expression and functional roles of the IGF?IGFBP system in reproductive organs. However, the disturbance of the IGF?IGFBP system in human reproductive physiology may lead to anovulation, disorders of androgen excess, infertility associated with implantation failure, and male infertility. Further research is needed in domestic animals to determine if manipulation of the IGF?IGFBP system may result in improved reproductive efficiency. As our understanding of the IGF?IGFBP system increases, the uses of human recombinant IGF peptides and IGFBPs as clinical therapy for disease states is becoming a reality. (Reprod Med Biol 2003; 2: 1?24) äInsulin?like growth factors and their binding proteins: Potential rele(epmc).pdf DeepDyve Pubget Overpricing